No time to sleep on it – start exercising!

Knowles, Olivia

doi:10.1113/jp279790

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…Despite employing a different stable isotope (phenylalanine vs. deuterated water), study design (acute cross-over design vs. chronic parallel design), and population (males and females vs. males only), our findings support those by Saner et al Negative phenotypic outcomes associated with a period of chronic sleep deprivation likely reflect a metabolic shift toward catabolism due to the accumulation of blunted anabolic responses to protein-containing meals and physical activity. Our group has further discussed the results and implications of the Saner paper elsewhere (Knowles, 2020).…”

Section: Acute Sleep Deprivation Decreases Muscle Protein Synthesismentioning

confidence: 98%

The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment

et al. 2021

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Acute and chronic sleep loss are linked with a range of negative physiological and psychological outcomes (Kecklund & Axelsson, 2016). While complete sleep deprivation rapidly impedes simple and complex cognitive functions, sleep restriction impairs whole-body homeostasis, leading to undesirable metabolic consequences in the short-and longer-term (Reutrakul & Van Cauter, 2018). Most metabolic tissues including liver (Shigiyama et al., 2018), adipose tissue (Wilms et al., 2019), and skeletal muscle are at risk of developing sleep loss-associated adverse outcomes.Skeletal muscle is a primary regulator of human metabolism. Sleep deprivation (Cedernaes et al., 2015(Cedernaes et al., , 2018 and restriction (Harfmann et al., 2015) have the potential to profoundly affect muscle health by altering gene regulation and substrate metabolism. Even relatively short periods of sleep restriction (less than a week) can compromise

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Section: Acute Sleep Deprivation Decreases Muscle Protein Synthesismentioning

confidence: 98%

The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment

et al. 2021

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“…Resistance exercise is an even more potent stimulus to promote MPS (18) and may constitute a better intervention to maintain muscle mass and function in sleep-restricted populations (19).…”

Section: Introductionmentioning

confidence: 99%

“…Saner et al (7) showed that high-intensity interval exercise may counteract the adverse effects of sleep restriction in males by maintaining myofibrillar protein synthesis rates at baseline levels. Resistance exercise is an even more potent stimulus to promote MPS (18) and may constitute a better intervention to maintain muscle mass and function in sleep-restricted populations (19). Resistance exercise is known to induce a large, but transient transcriptional response, which is thought to underpin the associated increases in strength and muscle mass (20).…”

Section: Introductionmentioning

confidence: 99%

The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females

Knowles,

Soria,

Saner

et al. 2024

Preprint

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IntroductionBoth sleep loss and exercise regulate gene expression in skeletal muscle, yet little is known about how the interaction of these stressors affects the transcriptome. The aim of this study was to investigate the effect of nine nights of sleep restriction, with repeated resistance exercise (REx) sessions, on the skeletal muscle transcriptome of young, trained females.MethodsTen healthy females aged 18-35 years undertook a randomised cross-over study of nine nights’ sleep restriction (SR; 5-h time in bed) and normal sleep (NS; ≥7 h time in bed) with a minimum 6-week washout. Participants completed four REx sessions per condition (day 3, 5, 7 and 9). Muscle biopsies were collected both pre- and post-REx on days 3 and 9. Gene and protein expression were assessed by RNA sequencing and Western Blot, respectively.ResultsThree or nine nights of sleep restriction had no effect on the muscle transcriptome independently of exercise. However, close to 3000 transcripts were differentially regulated (FDR < 0.05) 48 h post the completion of three resistance exercise sessions in both NS and SR conditions. Only 39% of downregulated and 18% of upregulated genes were common between both conditions, indicating a moderating effect of sleep restriction on the response to exercise.ConclusionSleep restriction and resistance exercise interacted to alter the enrichment of skeletal muscle transcriptomic pathways in young, resistance-trained females. Performing exercise when sleep restricted may not provide the same adaptive response for individuals as if they were fully rested.

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“…The three NREM and one REM phases occur cyclically throughout the night, typically taking 70–110 min to complete a full sleep cycle [ 4 ] ( Figure 1 ). Humans generally experience 4–7 sleep cycles per night, with different proportions of time spent in each stage throughout the night ( Figure 1 ), depending on factors such as sleep disorders, previous sleep habits, circadian desynchronisation, age, sex, and illness [ 5 ]. Typical sleep architecture is characterised by a larger proportion of time spent in NREM in the first half of the night, with REM becoming more frequent in the second half of the night ( Figure 1 ).…”

Section: Introductionmentioning

confidence: 99%

Pyjamas, Polysomnography and Professional Athletes: The Role of Sleep Tracking Technology in Sport

Driller

Dunican

Omond

et al. 2023

Sports

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Technological advances in sleep monitoring have seen an explosion of devices used to gather important sleep metrics. These devices range from instrumented ‘smart pyjamas’ through to at-home polysomnography devices. Alongside these developments in sleep technologies, there have been concomitant increases in sleep monitoring in athletic populations, both in the research and in practical settings. The increase in sleep monitoring in sport is likely due to the increased knowledge of the importance of sleep in the recovery process and performance of an athlete, as well as the well-reported challenges that athletes can face with their sleep. This narrative review will discuss: (1) the importance of sleep to athletes; (2) the various wearable tools and technologies being used to monitor sleep in the sport setting; (3) the role that sleep tracking devices may play in gathering information about sleep; (4) the reliability and validity of sleep tracking devices; (5) the limitations and cautions associated with sleep trackers; and, (6) the use of sleep trackers to guide behaviour change in athletes. We also provide some practical recommendations for practitioners working with athletes to ensure that the selection of such devices and technology will meet the goals and requirements of the athlete.

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No time to sleep on it – start exercising!

Cited by 6 publications

References 6 publications

The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment

The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment

The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females

Pyjamas, Polysomnography and Professional Athletes: The Role of Sleep Tracking Technology in Sport

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