NO-synthasis/arginasis System in Plasma and Blood Lymphocytes in Women with Primary Infertility and Recurrent Pregnancy Loss with Ascariasis Presence.

Abstract

Materials and methods : This is an investigation of 49 cases with confirmed ascariasis and pathology of reproductive system in the Lviv City Center for Family Planning and Human Reproduction Lviv Ukraine between January 2013 and December 2015.
 Purpose : The aim of the study was to investigate changes in the L-arginine / NO synthase / arginase system in women with primary infertility and recurrent pregnancy loss with ascariasis presence in Ukraine.
 Results : In women with recurrent pregnancy loss and women with primary infertility were observed significant activation of iNOS in lymphocyte lysates, an increase in nitrite anion production, and a decrease in L-arginine content in the blood plasma and ascariasis compared with RPL and PI patients without ascariasis. 
 Conclusion : Ascariasis can be factor of the development of inflammation.