No Survival Benefit With Wide Margin Mohs Micrographic Surgery for Melanoma: A National Cancer Database Analysis

Abstract

O ptimal treatment strategies for melanoma remain controversial, including resection margins in Mohs micrographic surgery (MMS). 1,2 MMS for melanoma is currently performed with varied techniques, including first-stage margins. 3 The objective of this study was to assess factors associated with margin utilization and outcomes of MMS with narrow versus wide margins for melanoma in situ (MIS) and malignant melanoma (MM).A retrospective analysis using the National x Cancer Database (NCDB) was performed; patients with MIS and MM undergoing MMS between 2004 and 2019 were included. Variables were categorized into patient (age, sex, comorbidity status, and insurance status) and lesion (location, histology, stage, and Breslow) characteristics for analysis; patient race was