No improvement in quality of life in children with epilepsy treated with the low glycemic index diet

Boles, Sama; Webster, Richard; Parnel, Sophie; Murray, Julie; Sell, Erick; Pohl, Daniela

doi:10.1016/j.yebeh.2019.106664

Cited by 3 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The following key points were highlighted from authors interviews with parents: (i) diet is a key component of family 332 ; (ii) perceptions of food, particularly fat, can change over time 332 ; and (iii) families want to know the real‐life impact the KD would have on their family life, from the supplies required to changes in shopping, KD preparation and the time required 304,330,335,336 . These research findings highlight the complexity of food and diet‐related medical treatments, and also indicate that little is known about children and KDs, in addition to why KDs are successful for some families and not others.…”

Section: Discussionmentioning

confidence: 99%

“…The remaining quantitative study designs included case series (10.7%, n = 34), descriptive survey (5.3%, n = 17), [299][300][301][302][303][304][305][306][307][308][309][310][311][312][313][314][315] ambispective cohort (2.5%, n = 8), [316][317][318][319][320][321][322][323] case-control (1.9%, n = 6) [324][325][326][327][328][329] and cross-sectional (0.6%, n = 2). 330,331 The remaining 1.6% (n = 5) were qualitative in design. [332][333][334][335][336] Where in the world has the research taken place?…”

Section: What Type Of Research Has Been Conducted?mentioning

confidence: 99%

See 1 more Smart Citation

The use of ketogenic diets in children living with drug‐resistant epilepsy, glucose transporter 1 deficiency syndrome and pyruvate dehydrogenase deficiency: A scoping review

Cameron,

Allan,

Kay Cooper

2024

J Human Nutrition Diet

View full text Add to dashboard Cite

BackgroundThe ketogenic diet (KD) is a high fat, moderate protein and very low carbohydrate diet. It can be used as a medical treatment for drug‐resistant epilepsy (DRE), glucose transporter 1 deficiency syndrome and pyruvate dehydrogenase deficiency. The aim of this scoping review was to map the KD literature, with a focus on epilepsy and associated metabolic conditions, to summarise the current evidence‐base and identify any gaps.MethodsThis review was conducted using JBI scoping review methodological guidance and the PRISMA extension for scoping reviews reporting guidance. A comprehensive literature search was conducted in September 2021 and updated in February 2024 using MEDLINE, CINAHL, AMED, EmBASE, CAB Abstracts, Scopus and Food Science Source databases.ResultsThe initial search yielded 2721 studies and ultimately, data were extracted from 320 studies that fulfilled inclusion criteria for the review. There were five qualitative studies, and the remainder were quantitative, including 23 randomised controlled trials (RCTs) and seven quasi‐experimental studies. The USA published the highest number of KD studies followed by China, South Korea and the UK. Most studies focused on the classical KD and DRE. The studies key findings suggest that the KD is efficacious, safe and tolerable.ConclusionsThere are opportunities available to expand the scope of future KD research, particularly to conduct high‐quality RCTs and further qualitative research focused on the child's needs and family support to improve the effectiveness of KDs.

show abstract

Section: Discussionmentioning

confidence: 99%