No evidence for measles, mumps, and rubella vaccine-associated inflammatory bowel disease or autism in a 14-year prospective study

Peltola, Heikki; Patja, Annamari; Leinikki, Pauli; Valle, M; Davidkin, Irja; Paunio, Mikko

doi:10.1016/s0140-6736(98)24018-9

Cited by 169 publications

(60 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…E.g Peltola et al (1998)) traces out all Finnish babies given the MMR since its introduction in 1982, all those who developed gastrointestinal side-effects lasting 24 hours or more. 31 children were identified and it was verified that all recovered and none developed any signs of autistic disorders.…”

Section: A Research Timelinementioning

confidence: 99%

Anatomy of a health scare: Education, income and the MMR controversy in the UK

Anderberg

Chevalier

Wadsworth

2011

Journal of Health Economics

View full text Add to dashboard Cite

One theory for why there is an education gradient in health outcomes is that more educated individuals more quickly absorb new health-related information. The measles, mumps, and rubella (MMR) controversy provides a case where, for a short period, some publicized research suggested that the particular childhood vaccine could have serious side-effects. As the controversy unfolded, uptake of the vaccine by more educated parents decreased relative to that of less educated parents, turning a positive education gradient into a negative one. We also consider the response in terms of uptake of other childhood vaccines and purchases of alternatives to the MMR.

show abstract

Section: A Research Timelinementioning

confidence: 99%

Anatomy of a health scare: Education, income and the MMR controversy in the UK

Anderberg

Chevalier

Wadsworth

2011

Journal of Health Economics

View full text Add to dashboard Cite

show abstract

“…Several large population-and ecologic-based studies were conducted over the following decade that consistently found no evidence of a link between the MMR vaccine and autism and failed to provide any support for Wakefield's theory [24][25][26][27]. In fact, the lack of an association between MMR vaccination and autism in children is supported by 19 additional scientific studies performed by diverse groups of investigators using various research methodologies involving disparate groups of patients over more than a decade [28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46]. Several of these studies have been discussed in detail in 4 review articles [47][48][49][50].…”

Section: Lack Of Evidence To Support the "Mmr Causes Autism" Theorymentioning

confidence: 99%

Vaccines and Autism – An Unlikely Connection

Chatterjee¹,

Moffatt²

2011

Autism - A Neurodevelopmental Journey From Genes to Behaviour

View full text Add to dashboard Cite

“…23 In contrast, MMR vaccination is remarkably safe. 24,25 In addition to the published studies cited here and the reviews at each meeting of the Committee on Safety of Medicines (CSM) and of the Joint Committee on Vaccination and Immunisation, comprehensive expert panels convened by the Medical Research Council (MRC) (twice), the CSM, the American Academy of Pediatrics, the Scottish Executive, the Irish Parliament, the British Medical Journal, the World Health Organization (WHO) and the Institute of Medicine (Washington, DC), have reviewed all the available evidence and all have concluded that there is no evidence of a link between MMR and autism. MMR vaccination does not cause autism.…”

Section: Measles Mumps and Rubella Vaccinationmentioning

confidence: 99%

Science and serendipity

Pepys

2007

Clinical Medicine

View full text Add to dashboard Cite

-Good science demands independent replication of new ideas and results and abandonment of accepted theories in light of more reliable evidence. Failure to comply leads to damaging bad science, as with the falsely claimed association between measles, mumps and rubella vaccination and autism. Progress of good science also often requires serendipity, 'making discoveries by accident and sagacity of things not sought'. Work on the pentraxin proteins, C-reactive protein (CRP) and serum amyloid P component (SAP), and on amyloidosis, has benefited from abundant serendipity, leading to routine clinical use of CRP measurements, the invention of SAP scintigraphy for amyloidosis, the establishment of the NHS National Amyloidosis Centre providing superior patient care, and latterly the invention of a novel pharmacological mechanism for therapeutic depletion of pathogenic proteins. New drugs using this mechanism are in development for amyloidosis and cardiovascular disease and potentially also Alzheimer's disease, type II diabetes and other tissue damaging conditions. KEY WORDS: amyloidosis, C-reactive protein, serum amyloid P component The nature of scienceWhat is science? An excellent definition is given by EO Wilson: 'Science is the systematic enterprise of gathering knowledge about the world and organising it and condensing that knowledge into testable laws and theories' . 1 In order for a claim or observation to be considered rigorously scientific it must be testable experimentally and must accurately predict how the relevant aspect of the world works. Robert Park, an eminent physicist and director of the Washington office of the American Physical Society, succinctly observes that if either condition is not met then: We all easily recognise commercial advertising but it is particularly important to identify advertising masquerading as science.Rigorous science and the scientific method are immensely powerful, and have been responsible for all progress in modern medicine and beyond. I will not provide examples or otherwise defend that statement in this College and before this audience because the case has been extensively rehearsed elsewhere, most recently in the outstanding 'Sense about Science' lecture given in March 2007 by Raymond Tallis. 4 Rather, I wish to focus on the difference between good science, which can be a majestic expression of the highest achievement of the human intellect and spirit, and bad science, which is misleading, wasteful, often damaging and sometimes lethal.A necessary condition for good science is that it must function within the strict guidelines of the s COLLEGE LECTURES 562

show abstract

No evidence for measles, mumps, and rubella vaccine-associated inflammatory bowel disease or autism in a 14-year prospective study

Cited by 169 publications

References 4 publications

Anatomy of a health scare: Education, income and the MMR controversy in the UK

Anatomy of a health scare: Education, income and the MMR controversy in the UK

Vaccines and Autism – An Unlikely Connection

Science and serendipity

Contact Info

Product

Resources

About