No effect of α‑GPC on lucid dream induction or dream content

Kern, Simon; Appel, Kristoffer; Schredl, Michael; Pipa, Gordon

doi:10.1007/s11818-017-0122-8

Cited by 8 publications

(11 citation statements)

References 23 publications

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“…In contrast to the positive findings for AChEIs, a double blind randomized placebocontrolled study found no significant effect of 1200 mg of the ACh precursor L-alpha glycerylphosphorylcholine (α-GPC) on the frequency of lucid dreams in 33 participants with varying degrees of lucid dreaming experience (Kern, Appel, Schredl and Pipa, 2017). One interpretation of this result is that, in contrast to AChEIs, α-GPC is not effective for inducing lucid dreams, perhaps due to differences in the neurobiological effects of cholinean ACh precursor-and AChEIs.…”

Section: Effects Of L-alpha Glycerylphosphorylcholine (α-Gpc) Lucid Dreamingmentioning

confidence: 83%

The cognitive neuroscience of lucid dreaming

Baird

Mota-Rolim

Dresler

2019

Neuroscience & Biobehavioral Reviews

132

139

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Lucid dreaming refers to the phenomenon of becoming aware of the fact that one is dreaming during ongoing sleep. Despite having been physiologically validated for decades, the neurobiology of lucid dreaming is still incompletely characterized. Here we review the neuroscientific literature on lucid dreaming, including electroencephalographic, neuroimaging, brain lesion, pharmacological and brain stimulation studies. Electroencephalographic studies of lucid dreaming are mostly underpowered and show mixed results. Neuroimaging data is scant but preliminary results suggest that prefrontal and parietal regions are involved in lucid dreaming. A focus of research is also to develop methods to induce lucid dreams. Combining training in mental set with cholinergic stimulation has shown promising results, while it remains unclear whether electrical brain stimulation could be used to induce lucid dreams. Finally, we discuss strategies to measure lucid dreaming, including best-practice procedures for the sleep laboratory. Lucid dreaming has clinical and scientific applications, and shows emerging potential as a methodology in the cognitive neuroscience of consciousness. Further research with larger sample sizes and refined methodology is needed.

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Section: Effects Of L-alpha Glycerylphosphorylcholine (α-Gpc) Lucid Dreamingmentioning

confidence: 83%

The cognitive neuroscience of lucid dreaming

Baird

Mota-Rolim

Dresler

2019

Neuroscience & Biobehavioral Reviews

132

139

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“…L‐alpha glycerylphosphorylcholine is one of the precursors of acetylcholine that can cross the brain–blood barrier (Kern et al, 2017). Compared with donepezil, which was analysed in the previous systematic review (i.e., Stumbrys et al, 2012), α‐GPC may have fewer side‐effects (Kern et al, 2017). The researchers provided two α‐GPC capsules, each containing 1.2 g α‐GPC, to each of the 40 participants.…”

Section: Resultsmentioning

confidence: 99%

“…Two of the 20 studies (Kern et al, 2017; LaBerge et al, 2018) used substances to induce lucid dreams in the participants, including L‐alpha glycerylphosphorylcholine (α‐GPC) and galantamine.…”

Section: Resultsmentioning

confidence: 99%

“…L-alpha glycerylphosphorylcholine is one of the precursors of acetylcholine that can cross the brain-blood barrier (Kern et al, 2017).…”

Section: L-alpha Glycerylphosphorylcholinementioning

confidence: 99%

“…Compared with donepezil, which was analysed in the previous systematic review (i.e., Stumbrys et al, 2012), α-GPC may have fewer side-effects (Kern et al, 2017). The researchers provided two α-GPC capsules, each containing 1.2 g α-GPC, to each of the 40 participants.…”

Section: L-alpha Glycerylphosphorylcholinementioning

confidence: 99%

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A systematic review of new empirical data on lucid dream induction techniques

Tan

Fan

2022

Journal of Sleep Research

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Lucid dreams are defined as dreams in which the dreamers are aware of the fact that they are dreaming as dreams continue. It has been $12 years since the last review of the efficiency of lucid dream induction techniques was conducted. Hence, the present study aimed to review the lucid dream induction techniques published in the past decade. The second aim was to propose a modified classification for the existing lucid dream induction techniques, including cognitive techniques, external stimulation, substance intervention, and cortical stimulation. The third aim was to assess the methodological quality of the studies included in the review. It was hypothesised that, comparing with the studies included in the last review, the studies included in the present review had better overall methodological quality. A total of 19 peerreviewed studies were included and analysed in the present review, from which 14 lucid dream induction techniques were identified. The results indicated that the

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Lucid Dreaming

Schredl¹

2018

Researching Dreams

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No effect of α‑GPC on lucid dream induction or dream content

Cited by 8 publications

References 23 publications

The cognitive neuroscience of lucid dreaming

The cognitive neuroscience of lucid dreaming

A systematic review of new empirical data on lucid dream induction techniques

Lucid Dreaming

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