1999
DOI: 10.1002/(sici)1098-2272(1999)16:1<54::aid-gepi5>3.0.co;2-s
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No common major gene for apolipoprotein A-I and HDL3-C levels: Evidence from bivariate segregation analysis

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Cited by 7 publications
(3 citation statements)
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“…The results were compatible with previous high risk population studies [18,19]. The reason is following.…”
Section: Discussionsupporting
confidence: 92%
“…The results were compatible with previous high risk population studies [18,19]. The reason is following.…”
Section: Discussionsupporting
confidence: 92%
“…Moreover, in other studies, a major-locus hypothesis was not conclusive, unless it was paired with HDL-C 10 or a second major locus was involved. 22 Recently, Livshits et al 15 found a major locus influencing plasma apo A-1 levels also influencing plasma HDL 3 -C concentrations in a random sample of 228 Israeli pedigrees; however, Juo et al 16 used 137 selected families ascertained through probands undergoing elective diagnostic coronary angiography at the Johns Hopkins Hospital and reported no common major locus for these phenotypes. In addition, 2 recent studies used the GAW8 Berkeley data set, 21 and the 137 selected families from the Johns Hopkins Hospital 22 have provided evidence of 2 major loci affecting apo A-1 levels.…”
Section: Discussionmentioning
confidence: 99%
“…Individual polymorphisms of apolipoprotein gene cluster, APOA1/C3/A4/A5 [3,[8][9][10][11][12] are located on chromosome 11 and N10 single nucleotide polymorphisms were found in this gene cluster [13]. Previous case-control association studies showed that APOA1 −75GNA polymorphism over the promoter site, was associated with HDL level [14,15].…”
Section: Introductionmentioning
confidence: 99%