volume 15, issue 1, P61-64 2020
DOI: 10.1007/s12104-020-09983-2
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Reiner Eidelpes, Hyeong Jin Kim, J. N. Mark Glover, Martin Tollinger

Abstract: Abstract In prokaryotic species, gene expression is commonly regulated by small, non-coding RNAs (sRNAs). In the gram-negative bacterium Legionella pneumophila, the regulatory, trans-acting sRNA molecule RocR base pairs with a complementary sequence in the 5’-untranslated region of mRNAs encoding for proteins in the bacterial DNA uptake system, thereby controlling natural competence. Sense-antisense duplexing of RocR with targeted mRNAs is mediated by the recently described RNA chaperone RocC. RocC contains a …

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