NMOSD with an unusual cerebral radiologic manifestation

Moghadasi, Abdorreza Naser; Altıntaş, Ayşe

doi:10.1016/j.msard.2016.03.016

Cited by 1 publication

(1 citation statement)

References 6 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…T2 lesions associated with AQP4‐ab are similar to those observed in MOGAD in terms of accompanying clinical severity and size but rarely resolve completely despite a large reduction in size. A prior study specifically analyzed brain lesion evolution on MRI in 63 NMOSD patients (95% AQP4‐ab‐positive), for a total of 211 acute brain lesions, observing complete resolution in 24% of these 123 …”

Section: Role Of Mri At Follow‐upmentioning

confidence: 99%

MRI to differentiate multiple sclerosis, neuromyelitis optica, and myelin oligodendrocyte glycoprotein antibody disease

Contentti

Okuda

Rojas³

et al. 2023

Journal of Neuroimaging

View full text Add to dashboard Cite

Differentiating multiple sclerosis (MS) from other relapsing inflammatory autoimmune diseases of the central nervous system such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is crucial in clinical practice. The differential diagnosis may be challenging but making the correct ultimate diagnosis is critical, since prognosis and treatments differ, and inappropriate therapy may promote disability. In the last two decades, significant advances have been made in MS, NMOSD, and MOGAD including new diagnostic criteria with better characterization of typical clinical symptoms and suggestive imaging (magnetic resonance imaging [MRI]) lesions. MRI is invaluable in making the ultimate diagnosis. An increasing amount of new evidence with respect to the specificity of observed lesions as well as the associated dynamic changes in the acute and follow‐up phase in each condition has been reported in distinct studies recently published. Additionally, differences in brain (including the optic nerve) and spinal cord lesion patterns between MS, aquaporin4‐antibody‐positive NMOSD, and MOGAD have been described. We therefore present a narrative review on the most relevant findings in brain, spinal cord, and optic nerve lesions on conventional MRI for distinguishing adult patients with MS from NMOSD and MOGAD in clinical practice. In this context, cortical and central vein sign lesions, brain and spinal cord lesions characteristic of MS, NMOSD, and MOGAD, optic nerve involvement, role of MRI at follow‐up, and new proposed diagnostic criteria to differentiate MS from NMOSD and MOGAD were discussed.

show abstract

Section: Role Of Mri At Follow‐upmentioning

confidence: 99%