“…Advantages of N 2 O include ease of administration; rapid onset and elimination; no biotransformation; easily titrated to desired effect; lack of flammability; absence of pungent odor; minimal cardiovascular or respiratory depressant effects; minimal systemic toxicity; lack of effect on hemoglobin oxygen desaturation, Apgar scores, and neonatal survival; and it does not trigger malignant hyperthermia [6][7][8][9][10][11][12]. Side effects of N 2 O include sweating, nausea, vomiting, dreaming, uncoordinated movements, sluggish response to verbal commands, laughing, excessive sleepiness, amnesia, and unconsciousness at higher concentrations (N70%) [6,[10][11][12]15,16]. These side effects are relatively rare when used at concentrations less than 40% [11].…”