1981
DOI: 10.1016/0006-8993(81)90245-6
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Nitrous oxide alters oxidative metabolic activities of rat neocortex in situ

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Cited by 5 publications
(2 citation statements)
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“…Rosenthal et al reported that in rats an increased oxidation of cytochrome a, as, occurs during N20 anaesthesia, suggesting an increased energy demand. 18 Pelligrino et al using a goat cerebrocortical mitochondrial preparation in vitro, observed that the increased 02 utilization during exposure to N20 may be due at least partly to a direct effect of N20 on mitochondrial respiration. 2 Under normal conditions, the brain is dependent upon a continuous supply of blood in order to obtain a continuous flow of 02 as well as glucose to the cells.…”
Section: N2/o2mentioning
confidence: 99%
“…Rosenthal et al reported that in rats an increased oxidation of cytochrome a, as, occurs during N20 anaesthesia, suggesting an increased energy demand. 18 Pelligrino et al using a goat cerebrocortical mitochondrial preparation in vitro, observed that the increased 02 utilization during exposure to N20 may be due at least partly to a direct effect of N20 on mitochondrial respiration. 2 Under normal conditions, the brain is dependent upon a continuous supply of blood in order to obtain a continuous flow of 02 as well as glucose to the cells.…”
Section: N2/o2mentioning
confidence: 99%
“…Also, N 2 O decreased the ratio of reduction/oxidation of cytochrome a , a 3 and it increased blood volume in rat brain, consistent with increased energy demand (Rosenthal et al . ). Similar cytochrome a , a 3 redox effects occur after cortical stimulation, and responses were attenuated by norepinephrine depletion by locus coeruleus lesion (Harik et al .…”
Section: Regulation Of Aerobic Glycolysis Via Adrenergic Receptorsmentioning
confidence: 97%