Nitrosoalkylureas derived from alkylammonium salts and their antitumor activity

Urea-based gemini surfactants: Synthesis, aggregation behaviour and biological activity

“…The 1-[2-(dimethylamino)ethyl]-3-undecylurea was prepared using a similar procedure as was used for the 1-cyclohexyl-3-[2-(dimethylamino)ethyl] urea [48] as follows. Into the ice-cooled stirred solution of 1-isocyanotoundecane (10 g, 35 mmol) in 25 mL of dry acetonitrile, 2.1 g (24 mmol) of 2-(N, N-dimethyl)ethane-1,2-diamine were added dropwise during 15 minutes.…”