Nitroglycerin-aggravated pre-eclamptic posterior reversible encephalopathy syndrome (PRES)

Posterior reversible encephalopathy syndrome—Insight into pathogenesis, clinical variants and treatment approaches

“…Aggravation of PRES with nitroglycerin has been described and this 327 drug should therefore be avoided [75,76]. Antiepileptic agents to be pre- …”

An intensive care approach to posterior reversible encephalopathy syndrome (PRES): An analysis of 7 cases

“…Fenoldopam mesylate is a selective dopamine-1 agonist that can also prevent renal failure. Nitroglycerin is also frequently used in such patients but was reported to aggravate brain edema by causing vasodilation in the brain (30). Sodium nitroprusside, hydralazine, diazoxide, and nimodipine, which is reported to have neuroprotective effects, may also be useful for lowering blood pressure (31,32).…”

Influenza A‐induced rhabdomyolysis and acute kidney injury complicated by posterior reversible encephalopathy syndrome

“…Continuous invasive blood pressure monitoring is advised as isolated measurements of blood pressure may be misleading. Despite their use in this case, others have warned against the use of nitrates for blood pressure control because of concerns regarding exacerbation of cerebral vasodilatation and oedema [17].…”