Nitrogen metabolism in Methanobacterium thermoautotrophicum: a solution and solid-state nitrogen-15 NMR study

Quantifying and directing metabolite flux: Application to amino acid overproduction

“…Although less spectacular, NMR studies have also been performed using the 2H [33] and ~SN [34,35] isotopes. The latter isotope, though very insensitive, was shown to be well-suited for quantification of nitrogen assimilation fluxes in competing enzyme reactions.…”