Nitro musk metabolites bound to carp hemoglobin: determination by GC with two MS detection modes: EIMS versus electron capture negative ion MS

Mottaleb, M. Abdul; Brumley, William C.; Sovocool, G. Wayne

doi:10.1080/03067310410001729033

Cited by 7 publications

(3 citation statements)

References 21 publications

(27 reference statements)

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“…In addition to the presence of Se-containing metabolites, other species such as urea, benzaldehyde, propylphenol, orotic acid, 3-nitrotyrosine, and 2-amino musk ketone were all possibly present in the group B sample. The organic components not associated with Se metabolites are marked as masses 1−6 whereas the Se-containing metabolites and fragments are labeled and listed as peaks A−H.…”

Section: Resultsmentioning

confidence: 53%

Analysis of Organoselenium and Organic Acid Metabolites by Laser Desorption Single Photon Ionization Mass Spectrometry

et al. 2006

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A method for analyzing organoselenium and organic acid metabolites using laser desorption from graphite surfaces coupled to vacuum ultraviolet single photon ionization mass spectrometry (LD/SPI MS) is described. The 1-10-fmol sensitivity and linear dynamic range allows quantitative detection of selenomethionine, trimethylselenonium ion, methylselenogalactosamine, and 1beta-methylseleno-N-acetyl-D-galactosamine in complex biological samples such as human urine. In addition, common urinary metabolites such as tartronic, glutaric, orotic, uric, suberic, and hydroxyhippuric acids, are readily detected. Screening and quantitative detection of these organoselenium and organic acid metabolites is achieved within minutes. The results are also consistent with those obtained using high-performance liquid chromatography tandem mass spectrometry techniques. The study demonstrates the viability of matrix-free LD/SPI MS for molecular characterization and quantitative analysis of biological metabolites in the m/z 10-500 range that are present in complex biological fluids.

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Section: Resultsmentioning

confidence: 53%

Analysis of Organoselenium and Organic Acid Metabolites by Laser Desorption Single Photon Ionization Mass Spectrometry

et al. 2006

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“…Musk (W. M) (synthetic musk), several chemical compounds were manufactured as Musk alternatives since they have Musk-like smell though differ in the chemical formula of Musk [29]. In the B. subtilis high sensitive Compared to the C. albicans2380,S.…”

Section: Discussionmentioning

confidence: 99%

Antagonistic Effect of Musk on Organisms Different Types

Aljuriss

ALNAJEM

ALGHOFAILI

et al. 2020

Int J Curr Pharm Sci

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Objective: This study aims to The research aimed at a comparative study the effect of natural and synthetic musk compared to creams that have an anti-fungal and anti-bacterial effect on the growth of Candida albicans that causes vaginal diseases in women, as well as the growth of the bacteria strains include Staphylococcus aureus, Bacillus subtilis, which would be more effective in inhibiting the growth of these microbes and Achieve the recommendation of the Prophet Muhammad for women to treat the vagina with natural musk, find alternatives to synthetic antibiotics, and reduce their negative effects on human health. Methods: This study investigates the antagonistic effect of Anti fungal and bacterial Cream and different natural type {Musk (N. M), Black Musk (B. M)} and chemical Musk {white Musk (W. M), cream Musk (M. C) } on some microorganisms. The types of yeast Candida albicans HVS and the bacteria strains include Staphylococcus aureus, Bacillus subtilis, were tested by means of disk diffusion, Results: Results indicated that Musk has inhibitory effects on the growth of study microorganisms Musk contains active substances similar to antibiotic, alkaloids and volatile oils present in them as they have the ability to stop the growth of many microorganisms. The effect of natural musk was higher than the effect synthetic musk, And the microbes were the most sensitive to musk is Bacillus subtilis. As for anti-microbial creams, the effect of the anti-bacterial cream was more effective in their suppression compared to all kinds of musk unlike the anti-fungal cream which gave a negative result. Conclusion: This study showed that the different concentrations of natural musk have an effective role in inhibiting some of the microbes of this vaginal pathogen, and it has given a positive opposite result to these microbes, and therefore it can be used as a natural antibiotic that reduces side effects on females and the environment.

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“…In several of the referenced studies EI-MS was employed, but as a result of a comparison study [31], we used NCI-MS. …”

Section: Gas Chromatography and Mass Spectrometrymentioning

confidence: 99%

Biotransformation of musk xylene in trout haemoglobin: dose–response and toxicokinetics of musk xylene metabolites haemoglobin adducts by gas chromatography-mass spectrometry

Mottaleb

Moy

Zimmerman

2006

International Journal of Environmental Analytical Chemistry

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Nitro musk metabolites bound to carp hemoglobin: determination by GC with two MS detection modes: EIMS versus electron capture negative ion MS

Cited by 7 publications

References 21 publications

Analysis of Organoselenium and Organic Acid Metabolites by Laser Desorption Single Photon Ionization Mass Spectrometry

Analysis of Organoselenium and Organic Acid Metabolites by Laser Desorption Single Photon Ionization Mass Spectrometry

Antagonistic Effect of Musk on Organisms Different Types

Biotransformation of musk xylene in trout haemoglobin: dose–response and toxicokinetics of musk xylene metabolites haemoglobin adducts by gas chromatography-mass spectrometry

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