Nitrite intoxication: Protection with methylene blue and oxygen

Controlled intravascular sodium nitroprusside treatment.

“…'7 Most had received prophylactic cranial irradiation (2400 rads), which may indirectly depress ovarian function via the hypothalamic pituitary axis. '8 Sherins et a14 have highlighted the vulnerability of the pubertal testis in a study of 21 Ugandan boys treated with quadruple chemotherapy for Hodgkin's disease. Nine of 19 survivors (all aged 11 or more when diagnosed) developed gynaecomastia a median of 28 months after treatment and had grossly raised FSH and LH and lowered testosterone concentrations indicating failure of the Leydig cells.…”