Nitric Oxide Photorelease from Ruthenium Salen Complexes in Aqueous and Organic Solutions

Abstract

The complexes [Ru(salen)(NO)Cl] and [Ru(salen)(NO)(H(2)O)](+) were shown to release the nitrosyl ligand as nitric oxide upon exposure to visible light in organic and aqueous solutions respectively, by means of UV-visible, EPR, and FTIR spectroscopies. The former was prepared by a new synthetic route and had its structure determined by single-crystal X-ray diffraction. A crystal of the dichloromethane solvate is orthorhombic, space group Fdd2 (No. 43) and formula C(16)H(14)ClN(3)O(3)Ru.CH(2)Cl(2), with Z = 16 and cell parameters a = 25.489(4), b = 33.435(4), and c = 9.3716(9) A. The electronic absorption spectra of the complexes were calculated using the INDO/S method. The water-soluble complex is a potential drug for antitumoral phototreatment.

Photo-Controlled Release of NO and CO with Inorganic and Organometallic Complexes

“…Ruthenium nitrosyl complexes are generally quite robust, and this thermal stability as well as the known photo-lability of such species has drawn considerable attention to these as possible photoNORMs [20,63,67,[87][88][89][90][91][92][93][94][95][96][97][98][99][100][101]. .…”

Gold nanoparticle modifies nitric oxide release and vasodilation in rat aorta

“…FT-IR is frequently used to characterize the oxidation state of the metal and NO ligands in ruthenium complexes [30]. The NO frequency of Cis-[Ru(bpy) 2 (NO)(4PySH)].…”

Synthesis and characterization of some new ruthenium (II) complexes as photosensitizers in dye-sensitized solar cells

“…The UV-Vis absorbance spectra of the studied complexes were recorded at room temperature using ethanol or DMF as a solvent and are shown in Fig. 2 and the assignments of the bands are reported in table 1 [29][30][31][32][33]. …”