Nitric oxide–cyclic guanosine monophosphate signaling in the local circuit of the cricket abdominal nervous system

Aonuma, Hitoshi; Kitamura, Yoshiichiro; Niwa, Koichi; Ogawa, Hiroto; Oka, Kotaro

doi:10.1016/j.neuroscience.2008.09.032

Cited by 9 publications

(3 citation statements)

References 75 publications

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“…In the present work, we use an NO electrode to detect NO release in the PC lobe. NO electrodes have been used in vertebrate brains in vivo and in slices [ 38 ], as well as in invertebrate neurons [ 39 – 41 ]. We then apply an NO synthase inhibitor to prove stimulus-evoked release of NO in olfactory responses.…”

Section: Introductionmentioning

confidence: 99%

Nitric Oxide-Mediated Modulation of Central Network Dynamics during Olfactory Perception

et al. 2015

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Nitric oxide (NO) modulates the dynamics of central olfactory networks and has been implicated in olfactory processing including learning. Land mollusks have a specialized olfactory lobe in the brain called the procerebral (PC) lobe. The PC lobe produces ongoing local field potential (LFP) oscillation, which is modulated by olfactory stimulation. We hypothesized that NO should be released in the PC lobe in response to olfactory stimulation, and to prove this, we applied an NO electrode to the PC lobe of the land slug Limax in an isolated tentacle-brain preparation. Olfactory stimulation applied to the olfactory epithelium transiently increased the NO concentration in the PC lobe, and this was blocked by the NO synthase inhibitor L-NAME at 3.7 mM. L-NAME at this concentration did not block the ongoing LFP oscillation, but did block the frequency increase during olfactory stimulation. Olfactory stimulation also enhanced spatial synchronicity of activity, and this response was also blocked by L-NAME. Single electrical stimulation of the superior tentacle nerve (STN) mimicked the effects of olfactory stimulation on LFP frequency and synchronicity, and both of these effects were blocked by L-NAME. L-NAME did not block synaptic transmission from the STN to the nonbursting (NB)-type PC lobe neurons, which presumably produce NO in an activity-dependent manner. Previous behavioral experiments have revealed impairment of olfactory discrimination after L-NAME injection. The recording conditions in the present work likely reproduce the in vivo brain state in those behavioral experiments. We speculate that the dynamical effects of NO released during olfactory perception underlie precise odor representation and memory formation in the brain, presumably through regulation of NB neuron activity.

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Section: Introductionmentioning

confidence: 99%

Nitric Oxide-Mediated Modulation of Central Network Dynamics during Olfactory Perception

et al. 2015

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“…Crickets detect air currents using filiform hairs that are arranged on the surface of the cerci of the abdomen, and respond with rapid avoidance movement when they are deflected (Edwards and Palka, 1974). Information on air movements is processed and integrated in the terminal abdominal ganglion, and the signals are transferred to the thoracic ganglia to initiate avoidance walking (Mendenhall and Murphey, 1974) (Aonuma et al, 2008) (Yono and Aonuma, 2008). Furthermore, the ascending signals from the abdominal nervous system also contribute to the initiation of walking; for example, after–defecation walking (Naniwa et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Descending and ascending signals that maintain rhythmic walking pattern in the cricket

Naniwa

Aonuma

2020

Preprint

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The cricket is one of the model animals used to investigate the neuronal mechanisms underlying adaptive locomotion. An intact cricket walks with a tripod gait, similar to other insects. The motor control center of the leg movements is located in the thoracic ganglia. In this study, we investigated the walking gait patterns of crickets whose ventral nerve cords were surgically cut to gain an understanding of how the descending signals from the head ganglia and ascending signals from the abdominal nervous system into the thoracic ganglia mediate the initiation and coordination of the walking gait pattern. Crickets whose paired connectives between the brain and subesophageal ganglion (SEG) were cut exhibited a tripod gait pattern. However, when one side of the connectives between the brain and SEG was cut, the crickets continued to turn in the opposite direction to the connective cut. Crickets whose paired connectives between the SEG and prothoracic ganglion were cut did not walk, whereas the crickets exhibited an ordinal tripod gait pattern when one side of the connectives was intact. Crickets whose paired connectives between the metathoracic ganglion and abdominal ganglia were cut initiated walking, although the gait was not a coordinated tripod pattern, whereas the crickets exhibited a tripod gait when one side of the connectives was intact. These results suggest that the brain plays an inhibitory role in initiating leg movements, and that both the descending signals from the head ganglia and the ascending signals from the abdominal nervous system are both important in initiating and coordinating insect walking gait patterns.

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“…Crickets detect air currents using filiform hairs that are arranged on the surface of the cerci of the abdomen and respond with rapid avoidance movement when they are deflected (Edwards and Palka, 1974). Information on air movements is processed and integrated into the terminal abdominal ganglion, and the signals are transferred to the thoracic ganglia to initiate avoidance walking (Mendenhall and Murphey, 1974;Aonuma et al, 2008;Yono and Aonuma, 2008). Furthermore, the ascending signals from the abdominal nervous system also contribute to the initiation of walking; for example, after-defecation walking (Naniwa et al, 2019).…”

Section: Descending Signals Into Thoracic Ganglia To Initiate Walkingmentioning

confidence: 99%

Descending and Ascending Signals That Maintain Rhythmic Walking Pattern in Crickets

Naniwa

Aonuma

2021

Front. Robot. AI

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The cricket is one of the model animals used to investigate the neuronal mechanisms underlying adaptive locomotion. An intact cricket walks mostly with a tripod gait, similar to other insects. The motor control center of the leg movements is located in the thoracic ganglia. In this study, we investigated the walking gait patterns of the crickets whose ventral nerve cords were surgically cut to gain an understanding of how the descending signals from the head ganglia and ascending signals from the abdominal nervous system into the thoracic ganglia mediate the initiation and coordination of the walking gait pattern. Crickets whose paired connectives between the brain and subesophageal ganglion (SEG) (circumesophageal connectives) were cut exhibited a tripod gait pattern. However, when one side of the circumesophageal connectives was cut, the crickets continued to turn in the opposite direction to the connective cut. Crickets whose paired connectives between the SEG and prothoracic ganglion were cut did not walk, whereas the crickets exhibited an ordinal tripod gait pattern when one side of the connectives was intact. Crickets whose paired connectives between the metathoracic ganglion and abdominal ganglia were cut initiated walking, although the gait was not a coordinated tripod pattern, whereas the crickets exhibited a tripod gait when one side of the connectives was intact. These results suggest that the brain plays an inhibitory role in initiating leg movements and that both the descending signals from the head ganglia and the ascending signals from the abdominal nervous system are important in initiating and coordinating insect walking gait patterns.

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Nitric oxide–cyclic guanosine monophosphate signaling in the local circuit of the cricket abdominal nervous system

Cited by 9 publications

References 75 publications

Nitric Oxide-Mediated Modulation of Central Network Dynamics during Olfactory Perception

Nitric Oxide-Mediated Modulation of Central Network Dynamics during Olfactory Perception

Descending and ascending signals that maintain rhythmic walking pattern in the cricket

Descending and Ascending Signals That Maintain Rhythmic Walking Pattern in Crickets

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