NIR Dye-Conjugated Maltodextrin for Photothermal Therapy of Cancer

Rampa, Dileep Reddy; Ko, Changgon; Lee, Yujin; Lee, Dongwon

doi:10.1007/s13233-021-9038-z

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Furthermore, this effect on the content of β-glucan was again shown to be more obvious in the SD samples than in those dried by freezing which is in line with the study conducted by Karthik and Anandharamakrishnan [ 96 ] showing the SD technique to be more efficient in the preservation of biologically active compounds in comparison with other employed encapsulation methods. Since MD is a hydrophilic polysaccharide consisting of D-glucose units linked primarily by α-(1 → 4) glycosidic linkages [ 97 , 98 ], the increase in the β-glucan concentration in our microencapsulated samples can be related to their unknown interactions. In this sense, it could be hypothesized that glucose units of the MD might interact with β-glucan functional groups of our powder during coating processes, thus increasing the β-glucan content in the dried samples.…”

Section: Discussionmentioning

confidence: 99%

Impact of Freeze- and Spray-Drying Microencapsulation Techniques on β-Glucan Powder Biological Activity: A Comparative Study

Valková

Ďúranová

Falcimaigne-Cordin

et al. 2022

Foods

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The study compares the impact of freeze- and spray-drying (FD, SD) microencapsulation methods on the content of β-glucan, total polyphenols (TP), total flavonoids (TF), phenolic acids (PA), and antioxidant activity (AA) in commercially β-glucan powder (Pleurotus ostreatus) using maltodextrin as a carrier. Morphology (scanning electron microscopy- SEM), yield, moisture content (MC), and water activity (aw) were also evaluated in the samples. Our examinations revealed significant structural differences between powders microencapsulated by the drying methods. As compared to non-encapsulated powder, the SD powder with yield of 44.38 ± 0.55% exhibited more reduced (p < 0.05) values for aw (0.456 ± 0.001) and MC (8.90 ± 0.44%) than the FD one (yield: 27.97 ± 0.33%; aw: 0.506 ± 0.002; MC: 11.30 ± 0.28%). In addition, the highest values for β-glucan content (72.39 ± 0.38%), TPC (3.40 ± 0.17 mg GAE/g), and TFC (3.07 ± 0.29 mg QE/g) have been detected in the SD powder. Our results allow for the conclusion that the SD microencapsulation method using maltodextrin seems to be more powerful in terms of the β-glucan powder yield and its contents of β-glucan, TP, and TF as compared to the FD technique.

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Section: Discussionmentioning

confidence: 99%