Ninjin'yoeito Modulates Baseline and Reperfusion‐Induced Changes in the Arteriole Diameter and Blood Flow in the Cerebral Cortex of Anesthetized Mice
Nobuhiro Watanabe,
Kaori Iimura,
Harumi Hotta
Abstract:ObjectiveIntragastric administration of ninjin'yoeito (NYT), a traditional Japanese herbal medicine, reportedly prevents the decrease in baseline cerebral blood flow (CBF) in the cortex following gastric administration of water. We investigated the effect of NYT on baseline and dynamic changes in cerebral cortical arteriole diameter.MethodsUrethane‐anesthetized mice were intragastrically administered 1 g/kg NYT or distilled water (DW). The artery in the left parietal cortex was imaged using two‐photon microsco… Show more
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