Nighttime Hypertension in Chronic Kidney Disease—Are We in the Dark Without Ambulatory Blood Pressure Monitoring?

Mayeda, Laura; Rivara, Matthew B.

doi:10.1001/jamanetworkopen.2022.14469

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…Sudden onset of SBH during night-time sleep is considered to be associated with a significant increase in nocturnal BP. Clinical guidelines recommend 24-h ambulatory BP monitoring in patients with CKD to detect nocturnal hypertension and to help clinicians to treat it with antihypertensive therapy (8,9).…”

Section: Discussionmentioning

confidence: 99%

Spontaneous brainstem haemorrhage in a patient with uraemia undergoing initial hemodialysis: A case report

Jia

Guo

2023

Exp Ther Med

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The present study reports the case of an elderly male inpatient with uraemia who had a sudden onset of numbness and weakness in the right limbs during sleep at night, accompanied by blurred and double vision, during the induction of haemodialysis (HD). Cranial computed tomography and magnetic resonance imaging revealed signs of brainstem haemorrhage. Consequently, a proactive treatment approach was adopted for decreasing the blood and intracranial pressures of the patient, and regular HD was continued. The condition of the patient improved, and the limbs showed no impairment of sensation, with normal movement. To the best of our knowledge, this is the first reported case of an inpatient with uraemia undergoing HD who developed a sudden brainstem haemorrhage during the induction phase of HD and completely recovered after conservative treatment. This unusual case deserves the attention of all clinicians, who should pay more attention to the patients with spontaneous brainstem hemorrhage.

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Section: Discussionmentioning

confidence: 99%

Spontaneous brainstem haemorrhage in a patient with uraemia undergoing initial hemodialysis: A case report

Jia

Guo

2023

Exp Ther Med

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“…Evidence shows that there are more chances of nocturnal HTN in hypertensive patients with CKD as compared to HTN without CKD. So nocturnal BP measurement is also important, which is only possible through ambulatory BP monitoring [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Blood Pressure Reducing Potential and Renoprotective Action of Cilnidipine Among Hypertensive Patients Suffering From Chronic Kidney Disease: A Meta-Analysis

Rohilla¹,

Sinha²,

Toppo³

et al. 2023

Cureus

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Hypertension is a risk factor for cardiovascular diseases which also causes progressive kidney damage leading to chronic kidney disease (CKD), so the rate of progression of CKD can be controlled by reducing blood pressure (BP). Many anti-hypertensive drugs are available. Cilnidipine is a new-generation calcium channel blocker (CCB). This meta-analysis is aimed to generate pooled evidence about the effectiveness of cilnidipine as an anti-hypertensive and to explore its reno-protective actions. Pubmed, Scopus, Cochrane Library, and Google Scholar were searched from January 2000 to December 2022 to include the studies. The pooled mean difference, along with 95% CI, was computed using Revman 5.4.1 software (Revman International, Inc., New York City, New York). The Cochrane risk-of-bias assessment tool was used for bias assessment. This meta-analysis was registered in PROSPERO with Reg. no. CRD42023395224. This metaanalysis included seven studies with 289 participants in the intervention group and 269 in the comparator group, and were selected from Japan, India, and Korea. Systolic blood pressure (SBP) was significantly reduced in cilnidipine treated group among hypertensives with CKD subjects weighted mean difference (WMD) was 4.33, and the 95% confidence interval (CI) was 1.26 to 7.31 as compared to the other group. Cilnidipine also shows a significant reduction in proteinuria with WMD 0.61 and 95% CI 0.42 to 0.80. Both groups were similar in adverse drug reactions (ADR). Cilnidipine is a more effective anti-hypertensive as compared to Amlodipine or other CCBs, mainly in reducing SBP. Besides this, cilnidipine also shows better reno-protective action because it also significantly reduces proteinuria in such patients.

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Nighttime Hypertension in Chronic Kidney Disease—Are We in the Dark Without Ambulatory Blood Pressure Monitoring?

Abstract: Hypertension is common in patients with chronic kidney disease (CKD) and is one of the most important modifiable risk factors for cardiovascular morbidity and mortality in this population. The 2021 revision of the Kidney Disease: Improving Global Outcomes (KDIGO) guideline for blood

Cited by 2 publications

References 9 publications

Spontaneous brainstem haemorrhage in a patient with uraemia undergoing initial hemodialysis: A case report

Spontaneous brainstem haemorrhage in a patient with uraemia undergoing initial hemodialysis: A case report

Blood Pressure Reducing Potential and Renoprotective Action of Cilnidipine Among Hypertensive Patients Suffering From Chronic Kidney Disease: A Meta-Analysis

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