1937
DOI: 10.1056/nejm193701142160202
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Night Blindness Due to Vitamin A Deficiency: A Consideration of Its Importance in Traffic Problems

Abstract: operations should have died is evidence of bad obstetrics. Elective cesarean sections were done for specious reasons. Some were done on badly infected cases. It is interesting to note that no craniotomies were found in this whole series.A report such as this is depressing. Good obstetrics is practiced in Boston, but this report brings out the fact that there is also a good deal of bad obstetrics. The results of this study are a direct challenge to those men that have done poor work, and it is their duty to per… Show more

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Cited by 19 publications
(4 citation statements)
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“…"writers, that with the close association known to exist between vitamin A and visual purple, it might be possible to show a relationship between vitamin A content in diet and recovery time from glare stimulation. The demonstration of this relationship would be an important step m the attack upon the problem of night accidents That the rate of dark adaptation can be altered by changes in the vitamin A intake has been demonstrated by other investigators (Jeghers, 1938, Hecht and Mandelbaum, 1939, "Wald and Stevens, 1939 The present study differs from these investigations m several respects In the first place, the method of measuring the eyes' recovery from light stimulation by means of the photometer or some adaptation of it is too complex and requires too much time for this instrument to be used on the wide scale testing demanded in the examining of hundreds of thousands of automobile drivers Consequently, a similar method, requiring only a few minutes of testing time, is needed Secondly, changes in the vitamin A intake through changes in the diet of the subjects, as contrasted with administering vitamin A concentrates, needed to be studied. It was thought that any wide use of vitamin A therapy in the treatment of automobile drivers suffering from glare weakness could be best accomplished through correct regulation of dietary requirements.…”
mentioning
confidence: 86%
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“…"writers, that with the close association known to exist between vitamin A and visual purple, it might be possible to show a relationship between vitamin A content in diet and recovery time from glare stimulation. The demonstration of this relationship would be an important step m the attack upon the problem of night accidents That the rate of dark adaptation can be altered by changes in the vitamin A intake has been demonstrated by other investigators (Jeghers, 1938, Hecht and Mandelbaum, 1939, "Wald and Stevens, 1939 The present study differs from these investigations m several respects In the first place, the method of measuring the eyes' recovery from light stimulation by means of the photometer or some adaptation of it is too complex and requires too much time for this instrument to be used on the wide scale testing demanded in the examining of hundreds of thousands of automobile drivers Consequently, a similar method, requiring only a few minutes of testing time, is needed Secondly, changes in the vitamin A intake through changes in the diet of the subjects, as contrasted with administering vitamin A concentrates, needed to be studied. It was thought that any wide use of vitamin A therapy in the treatment of automobile drivers suffering from glare weakness could be best accomplished through correct regulation of dietary requirements.…”
mentioning
confidence: 86%
“…Tansley (1933) has shown that the concentration of visual purple m the retinas of rats and dogs, which have been subjected to a vitamin A deficient diet, is very low and ma} r be totally absent She (1931) previously had presented evidence which indicated that vitamin A is a precursor of visual purple, and that the amount of visual purple in the eye at any given 369 time is in part conditioned upon the amount of vitamin A present. Some investigators have used the relationship between the rate of recovery following stimulation with a bright light and vitamin A as a basis for detecting subclinical states of vitamin A deficiency (Jeans and Zentmire, 1934;Park, 1936;Jeans, Blanchard, and Zentmire, 1937;Jeghers, 1937;Hecht and Mandelbaum, 1939;Wald and Stevens, 1939) In the report of Jeans and Zentmire (1934), 21% of a group of 213 children were considered to be suffering from avitaminosis A On testing 275 adults, Park (1936) found two in a group considered to be vitamin A deficient who also experienced difficulties when driving at night due to the glare of the headlights of approaching cars Some of Jeghers' (1937) subjects also experienced similar difficulties On questioning those individuals who had long recovery times, several of them reported that they preferred not to do any night driving because of experiencing relatively long periods of blindness from the headlights of approaching cars In a later and more extensive study (1938) those subjects having difficulties in night driving were given large doses of vitamin A concentrates They all gained relief and could again drive at night with little ill effect from glaring headlights In these investigations the photometer or some adaptation of it was used, and the measure of the dark adaptation rate was the rate of change in the threshold for absolute intensity following stimulation with a very bright light. The present writers became interested in the relationship between glare weakness and vitamin A intake in connection with studies on the factors conditioning efficiency in automobile driving.…”
mentioning
confidence: 99%
“…Several writers have pointed out the important role that night blindness plays in automobile accidents after dark (29,36,37,42). Although a number of devices have been developed to measure adaptation to the dark, time of recovery from glaring lights, and ability to see in the face of glaring lights, little has been done to correlate these three different types of tests and to determine how important normal night vision and normal glare vision are in driving a car after dark.…”
Section: Review Of the Literaturementioning
confidence: 99%
“…A high proportion of flying accidents occur at night, and of motoring accidents at twilight. Delayed dark adaptation is probably of importance also with reference to dazzling by strong head-lamps (Jeghers, 1937). The problem is therefore not of merely academic interest.…”
Section: Practical Aspectsmentioning
confidence: 99%