Nicotinamide adenine dinucleotide immobilized tungsten trioxide nanoparticles for simultaneous sensing of norepinephrine, melatonin and nicotine

Anithaa, A.C.; Lavanya, N.; Sekar, C.

doi:10.1016/j.bios.2019.111598

Cited by 15 publications

(6 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The sensor displayed a negligible response toward the interfering analytes, thus displaying an excellent anti-interference property of the fabricated Bi 2 WO 6 sensor. This can be attributed to the oxidation potentials of dopamine, UA, epinephrine, K + , Na + , and LA, which are much higher than the oxidation potential of nicotine . At the applied potential of 20 mV, nicotine gets oxidized to 5′ hydroxy nicotine in the presence of Bi 2 WO 6 due to its excellent photocatalytic nature, whereas other interfering analytes do not interfere with the response of nicotine due to the requirement of higher oxidation potentials for oxidation of the analytes.…”

Section: Resultsmentioning

confidence: 99%

“…This can be attributed to the oxidation potentials of dopamine, 23 UA, epinephrine, K + , Na + , and LA, which are much higher than the oxidation potential of nicotine. 24 At the applied potential of 20 mV, nicotine gets oxidized to 5′ hydroxy nicotine in the presence of Bi 2 WO 6 due to its excellent photocatalytic nature, whereas other interfering analytes do not interfere with the response of nicotine due to the requirement of higher oxidation potentials for oxidation of the analytes. Differential pulse voltammetry (DPV) studies were performed to analyze the oxidation potential of nicotine upon interaction with a Bi 2 WO 6 sensor.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Biconcave Bi₂WO₆ Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples

Veeralingam

Badhulika

2020

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

We report a single-step hydrothermal synthesis of morphologically engineered biomimetic three-dimensional (3D) biconcave-shaped Bi 2 WO 6-nanostructures for photo-enhanced ultrasensitive determination of nicotine in human sweat and cigarette samples. Detailed characterization reveals the formation of orthorhombic, red blood cell-mimicking Bi 2 WO 6 nanoparticles. The average diameter of the biconcave Bi 2 WO 6 nanoparticles ranged from 50 to 100 nm. The fabricated sensor displayed a sensitivity of 56.97 ± 2 μM −1 in the wide linear range of 50 nM− 100 μM, with a limit of detection (LOD) of 13 nM (3σ) when exposed to nicotine. An enhanced sensitivity of 83.23 ± 1 μM −1 and a reduced LOD of 0.9 nM in the presence of UV light can be attributed to the outstanding sensing response of nicotine in the presence of UV light due to the synergistic−catalytic and photoresponsive properties of large-surface-area Bi 2 WO 6 nanostructures. The photoinduced oxygen ions react with the adsorbed oxygen atoms assisting in the formation of O 2− ions, which further contributes to the enhanced interaction with nicotine. The sensor displayed excellent selectivity toward nicotine in the presence of interferences and was robust to bending conditions, thus bolstering its practical applicability. Further, the sensor was employed in determining the unknown concentrations of nicotine in sweat and commercially available cigarettes. The strategy employed here expands the scope of photo-activated flexible nanoelectronic devices to develop affordable platforms for sensing various bioanalytes.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Biconcave Bi₂WO₆ Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples

Veeralingam

Badhulika

2020

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

show abstract

“…SWV was applied due to its suitability, selectivity, and sensitivity; this technique facilitated the electrocatalytic analysis of melatonin, norepinephrine, and nicotine in the presence of various biomolecules that would potentially cause interference in in vivo samples, such as dopamine, serotonin, epinephrine, cotinine, adenosine diphosphate, adenosine triphosphate, glucose, folic acid, tyrosine, tryptophan, UA, cysteine, and AA. 125 The LODs for melatonin, norepinephrine, and nicotine were 2.6 nM, 1.4 nM, and 1.7 nM, respectively. In the same study, sensitive GCEs modified with γ ray-irradiated ethylenediaminetetraacetic acid-WO 3 nanoparticles harboring immobilized NAD were developed for melatonin detection.…”

Section: Swv-based Detection Of Melatoninmentioning

confidence: 94%

“…The sensor comprised nicotinamide adenine dinucleotide (NAD) immobilized on gamma (γ)-irradiated tungsten trioxide nanoparticles (WO 3 ), which was used to coat a GCE (Figure 4). 125 The nicotinamide coenzyme is required to catalyze the reversible NAD + to NADH redox reaction, which is a major source of energy production during cellular respiration. 126 The strong redox properties of the deposited NAD enabled the differential electro-oxidation of melatonin, norepinephrine, and nicotine, thus enabling the identification and quantification of the three analytes.…”

Section: Swv-based Detection Of Melatoninmentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensors for Detecting Tryptophan and Melatonin

Khan¹,

Hong²,

Lee³

et al. 2021

IJN

View full text Add to dashboard Cite

Tryptophan and melatonin are pleiotropic molecules, each capable of influencing several cellular, biochemical, and physiological responses. Therefore, sensitive detection of tryptophan and melatonin in pharmaceutical and human samples is crucial for human wellbeing. Mass spectrometry, high-performance liquid chromatography, and capillary electrophoresis are common methods for both tryptophan and melatonin analysis; however, these methods require copious amounts of time, money, and manpower. Novel electrochemical and optical detection tools have been subjects of intensive research due to their ability to offer a better signal-to-noise ratio, high specificity, ultra-sensitivity, and wide dynamic range. Recently, researchers have designed sensitive and selective electrochemical and optical platforms by using new surface modifications, microfabrication techniques, and the decoration of diverse nanomaterials with unique properties for the detection of tryptophan and melatonin. However, there is a scarcity of review articles addressing the recent developments in the electrochemical and optical detection of tryptophan and melatonin. Here, we provide a critical and objective review of high-sensitivity tryptophan and melatonin sensors that have been developed over the past six years (2015 onwards). We review the principles, performance, and limitations of these sensors. We also address critical aspects of sensitivity and selectivity, limit and range of detection, fabrication process and time, durability, and biocompatibility. Finally, we discuss challenges related to tryptophan and melatonin detection and present future outlooks.

show abstract

“…Several research groups have proposed the use of these immobilized cofactors, particularly nicotinamide derivatives, for various applications. Lowe et al 25 reported the purification of nicotinamide nucleotide-dependent dehydrogenases on immobilized cofactors, while Anithaa et al 26 described the synthesis of gamma-irradiated EDTA-WO 3 -modified GCEimmobilized NAD for electrode fabrication. However, very few studies have developed green syntheses, and mostly relied on synthetic approaches requiring multiple atom-consuming protections and substrate deprotection steps.…”

Section: ■ Introductionmentioning

confidence: 99%

Immobilization of Adenosine Derivatives onto Cellulose Nanocrystals via Click Chemistry for Biocatalysis Applications

Bourgery,

Mendoza,

Garnier

et al. 2024

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

Adenosine triphosphate (ATP) is a central molecule of organisms and is involved in many biological processes. It is also widely used in biocatalytic processes, especially as a substrate and precursor of many cofactors�such as nicotinamide adenine dinucleotide phosphate (NADP(H)), coenzyme A (CoA), and S-adenosylmethionine (SAM). Despite its great scientific interest and pivotal role, its use in industrial processes is impeded by its prohibitory cost. To overcome this limitation, we developed a greener synthesis of adenosine derivatives and efficiently selectively grafted them onto organic nanoparticles. In this study, cellulose nanocrystals were used as a model combined with click chemistry via a copper-catalyzed azide/alkyne cycloaddition reaction (CuAAC). The grafted adenosine triphosphate derivative fully retains its biocatalytic capability, enabling heterobiocatalysis for modern biochemical processes.

show abstract

Nicotinamide adenine dinucleotide immobilized tungsten trioxide nanoparticles for simultaneous sensing of norepinephrine, melatonin and nicotine

Cited by 15 publications

References 31 publications

Biconcave Bi₂WO₆ Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples

Biconcave Bi₂WO₆ Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples

Recent Advances in Electrochemical and Optical Sensors for Detecting Tryptophan and Melatonin

Immobilization of Adenosine Derivatives onto Cellulose Nanocrystals via Click Chemistry for Biocatalysis Applications

Contact Info

Product

Resources

About

Nicotinamide adenine dinucleotide immobilized tungsten trioxide nanoparticles for simultaneous sensing of norepinephrine, melatonin and nicotine

Cited by 15 publications

References 31 publications

Biconcave Bi2WO6 Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples

Biconcave Bi2WO6 Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples

Recent Advances in Electrochemical and Optical Sensors for Detecting Tryptophan and Melatonin

Immobilization of Adenosine Derivatives onto Cellulose Nanocrystals via Click Chemistry for Biocatalysis Applications

Contact Info

Product

Resources

About

Biconcave Bi₂WO₆ Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples

Biconcave Bi₂WO₆ Nanoparticles for UV Light-Activated Detection of Nicotine in Human Sweat and Cigarette Samples