Nicolau′s syndrome following diclofenac administration: A report of two cases

Late development Nicolau Syndrome: A case report

“…The lesion in the tissue is reversible and quick working therapy with vasoactive substances such as subcutaneous heparin has proven to be beneficial [14].…”

“…According to Murthy, Siddalingappa and Suresh (2007), the conservative treatment with debridement and pain control constitute the main therapy [14].…”

“…Intravenous betamethasone, dexamethasone or methylprednisolone) and vasoactive therapy (i.e. pentoxifilline) [14].…”

Síndrome de Nicolau de desenvolvimento tardio: relato de caso

“…14 Considering the fact that there is no set standard for the treatment of the Nicolau syndrome it is important that the use of a correct technique for injection to minimize the risk factors. Prior aspiration is important to ensure an extra-articular injection.…”

“…14 According to Murthy, Siddalingappa & Suresh (2007), conservative treatment with debridement and pain control is the main therapy. 14 Considering the fact that there is no set standard for the treatment of the Nicolau syndrome it is important that the use of a correct technique for injection to minimize the risk factors.…”