Abstract:Allergic contact dermatitis to nickel is a global health problem. Worldwide, nickel continues to be the most prevalent and relevant contact allergen detected in tested populations for the last 30 years. Thus, the need for nickel-free products is palpable. We present a sustainable resource to aid providers and consumers in locating a wide variety of nickel free alternatives.
“…Food items like chocolate and many other products, such as zippers, buttons, cell phones, orthodontic braces and eyeglass frames may contain nickel. For example, objects with sentimental value (heirlooms, wedding rings) could be treated with an enamel or rhodium plating [80].…”
Nickel is a transition element extensively distributed in the environment, air, water, and soil. It may derive from natural sources and anthropogenic activity. Although nickel is ubiquitous in the environment, its functional role as a trace element for animals and human beings has not been yet recognized. Environmental pollution from nickel may be due to industry, the use of liquid and solid fuels, as well as municipal and industrial waste. Nickel contact can cause a variety of side effects on human health, such as allergy, cardiovascular and kidney diseases, lung fibrosis, lung and nasal cancer. Although the molecular mechanisms of nickel-induced toxicity are not yet clear, mitochondrial dysfunctions and oxidative stress are thought to have a primary and crucial role in the toxicity of this metal. Recently, researchers, trying to characterize the capability of nickel to induce cancer, have found out that epigenetic alterations induced by nickel exposure can perturb the genome. The purpose of this review is to describe the chemical features of nickel in human beings and the mechanisms of its toxicity. Furthermore, the attention is focused on strategies to remove nickel from the environment, such as phytoremediation and phytomining.
“…Food items like chocolate and many other products, such as zippers, buttons, cell phones, orthodontic braces and eyeglass frames may contain nickel. For example, objects with sentimental value (heirlooms, wedding rings) could be treated with an enamel or rhodium plating [80].…”
Nickel is a transition element extensively distributed in the environment, air, water, and soil. It may derive from natural sources and anthropogenic activity. Although nickel is ubiquitous in the environment, its functional role as a trace element for animals and human beings has not been yet recognized. Environmental pollution from nickel may be due to industry, the use of liquid and solid fuels, as well as municipal and industrial waste. Nickel contact can cause a variety of side effects on human health, such as allergy, cardiovascular and kidney diseases, lung fibrosis, lung and nasal cancer. Although the molecular mechanisms of nickel-induced toxicity are not yet clear, mitochondrial dysfunctions and oxidative stress are thought to have a primary and crucial role in the toxicity of this metal. Recently, researchers, trying to characterize the capability of nickel to induce cancer, have found out that epigenetic alterations induced by nickel exposure can perturb the genome. The purpose of this review is to describe the chemical features of nickel in human beings and the mechanisms of its toxicity. Furthermore, the attention is focused on strategies to remove nickel from the environment, such as phytoremediation and phytomining.
“…NMR spectra were recorded on a Brücker Avance 400 spectrometer at room temperature. 1 H frequency was at 400 MHz and 13 C frequency was at 100 MHz. 1 H and 13 C NMR data match that reported in the literature.…”
Section: Methodsmentioning
confidence: 99%
“…1 H frequency was at 400 MHz and 13 C frequency was at 100 MHz. 1 H and 13 C NMR data match that reported in the literature.…”
Section: Methodsmentioning
confidence: 99%
“…The anthropogenic activities using Ni have led to the release of significant amounts of Ni and derivatives into the environment. Ni pollution of the soil–water continuum is serious since long-term exposure to high concentrations of Ni can cause dermatitis, 1 asthma, 2 cardiovascular and kidney diseases, lung fibrosis, 3 lung and nasal cancers. 4 Exposure to Ni pollution mainly concerns oral ingestion through water and food.…”
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