Abstract:We
report a three-component olefin reductive dicarbofunctionalization for
constructing densely functionalized alkylborates, specifically,
nickel-catalyzed reductive dialkylation and alkylarylation of vinyl boronates
with a variety of alkyl bromides and aryl iodides. This reaction exhibits good
coupling efficiency and excellent functional group compatibility, providing
convenient access to the late-stage modification of complex natural products
and drug molecules. Combined with versatile alkylborate transformat… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.