Herein, we developed an efficient and transition-metal-free
multicomponent
coupling reaction for the synthesis of aroyloxyl alkyl iodides. In
the reaction among 2,4,6-triarylboroxines, THF, TMSCF3,
LiOH, and NaI, five-component reactions could be precisely controlled
by modulating CF3SO2Na, supplying one type of
aroyloxyl alkyl iodides in moderate to high yields. The reaction exhibits
good functional group tolerance and a wide substrate scope and can
be easily transformed into other useful compounds. The mechanism is
proposed on the basis of the control experiments