“…Treatment did not affect the routine laboratory parameters, which were comparable to those reported in previous studies 11,12,15,25,28,36,42 . In this study, sodium nitroprusside was used for hypotension because of its pharmacokinetic advantages in easily maintaining MAP as required, however, hypotension has been induced successfully by various pharmacological agents, so many other drugs are available for its routine induction during orthognathic surgery 7,15,19,28,32,40 .…”