nhibition of Melanin Synthesis by Mycelial Culture Broth of Paecilomyces japonica in the Mulberry

Park, Sang-Sang; Ryu, Young-Bae; Lee, Young-Hoon; Cho, Yong-Un; Cho, Soo‐Jeong; Choi, Young-Ju; Park, Ki-Hoon; Gal, Sang Wan

doi:10.5352/jls.2007.17.6.816

Cited by 8 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…넓은 범위의 동충하초 속 이 있지만 모든 종류가 약용으로 사용되는 것은 아니며 그 대표적인 것은 Paecilomyces japonica (P. japonica)와 Cordyceps militaris (C. militaris)이다. P. japonica 는 국내에서 고유하게 개발된 품종으로 눈꽃 동충하초라 부르고 나방류의 곤충과 애벌레, 번데기등을 기주로 하여 기생하며 항암효과, 면역증 강효과, 항 피로효과, 항 스트레스효과, 항 노화효과, 미백효과 등이 보고되고 있다 [27]. 또한 C. militaris 는 번데기 동충하초 라 부르며 나비목의 번데기에 기생하는 자실체와 번데기의 복합체로 P. japonica 와 마찬가지로 면역증강활성, 항암활성, 항바이러스효과 및 항염증 효과 등 다양한 생리활성이 보고 됨에 강장 식품 혹은 강장제로 폭넓게 사용되고 있다 [1].…”

Section: 서 론unclassified

Antioxidative Activity and Chemical Characteristics of Cordycepin-enriched Cordyceps militaris JLM0636 Powder

Ahn¹,

Cha²,

Jeong³

et al. 2013

Journal of Life Science

View full text Add to dashboard Cite

The antioxidative activity and bioactivity of water, ethanol, and methanol extracts from Paecilomyces japonica (PJ), Cordyceps militaris (CM), and cordycepin-enriched C. militaris JLM0636 (CMα) were tested in in vitro experimental models. The PJ water extract showed the highest extraction yield (42.53%). The highest content of phenolic compounds and flavonoids were found in the water extract of PJ, 2.72% and 1.73%, respectively. The major minerals were K, Mg, and Ca. The water extracts of PJ also showed the highest DPPH free radical scavenging activity and reducing power. Linoleic acid peroxidation and antioxidative activities were strong in CMα. The methanol extracts of PJ showed the highest inhibition activity against tyrosinase. Fibriolytic activity was higher in CMα than in CM. These results may provide basic data to understand the biological activities of bioactive materials derived from CMα for the development of functional foods, cosmetics, and antithrombotics.

show abstract

Section: 서 론unclassified

Antioxidative Activity and Chemical Characteristics of Cordycepin-enriched Cordyceps militaris JLM0636 Powder

Ahn¹,

Cha²,

Jeong³

et al. 2013

Journal of Life Science

View full text Add to dashboard Cite

show abstract

“…Interestingly, compared to the mycelium cultured in the existing general medium, some natural products have been shown to have more active compounds and better biological activities. Previous studies using mulberry (12) and medicinal herbs (13) as natural media for mycelium cultivation showed an increase in biological activities. Rhynchosia nulubilis can be used as a medium for cultivation because it contains valuable nutrients.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and Anti-Inflammatory Activity and Cytotoxicity of Ethanol Extracts from Rhynchosia nulubilis Cultivated with Ganoderma lucidum Mycelium

Park¹,

Kim²

2018

pnf

View full text Add to dashboard Cite

In this study, in order to verify the use of mycelium as a new functional material, Rhynchosia nulubilis was cultivated with Ganoderma lucidum mycelium, and the biological activity of the culture extract was evaluated. Measurements of the 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt radical scavenging activity showed that the ethanol extract from Rhynchosia nulubilis cultivated with Ganoderma lucidum mycelium (RNGM) had significantly higher radical scavenging activity compared to the ethanol extract from Rhynchosia nulubilis (RN). The growth inhibition rate of RNGM against HeLa cells was 93.93% at 400 μg/mL in the 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyl tetrazolium assay. RNGM effectively decreased nitric oxide production in lipopolysaccharide-treated RAW264.7 macrophage cells. The total polyphenol, total flavonoid, and the β-glucan contents of RNGM were higher than those of RN. These results demonstrated that increased total polyphenols, flavonoids, and β-glucan of Rhynchosia nulubilis during cultivation with the Ganoderma lucidum mycelium could increase the antioxidant and anti-inflammatory activity and cytotoxicity of cancer cells.

show abstract

“…인류는 예로부터 천연물을 질병 치료를 위한 의약품 원료로 요 긴하게 사용해 오고 있으며, 최근에는 화장품, 건강 기능성 식품 의 개발을 위해 다양하게 이용하고 있다 (Kim et al, 2011a (Chan & Kim, 2011;Han et al, 2006 (Shin et al, 2008 (Brown & Shalita, 1998;Koreck et al, 2003;Park et al, 2008a).…”

Section: Introductionunclassified

Trends in the Efficacy and Safety of Ingredients in Acne Skin Treatments

Lee¹,

Son²

2018

Asian J Beauty Cosmetol

View full text Add to dashboard Cite

The aim of this study is to explore trends in safety and efficacy of ingredients used in treatments for acne at a time when the distrust of chemicals is growing. 'Acne' is a chronic inflammatory follicular disorder of the skin. Propionibacterium acnes (P. acnes) plays critical roles in the outbreak of acne by inducing inflammation and forming comedones. Currently, the main methods of treatment for acne vulgaris include oral antibiotics, anti-inflammatory drugs, retinoids, and topical medication. However, prolonged use of these drugs can cause side effects such as skin irritation, dryness, flushing, itching, and resistance to the drug. Thus, there is a demand for effective natural alternatives. Natural extracts that reduce bacterial activity to treat acne are expected to have significantly fewer side effects than existing medications. According to studies anti-bacterial effects are such as Nelumbo nucifera G., Corni fructus , Persicaria perfoliata , Taraxacum mongolicum H., Phragmitis rhizoma , Agrimonia pilosa , Lavandula offcinalis , Cymbopogon martini , Menthapiperita , Eucalyptus globulus, Camellia japonica, ceramide, propolis, epidermal growth factor (EGF) and so on. Further tests of the safety and efficacy of natural extracts with antibacterial properties compared to existing acne medications are needed.

show abstract

nhibition of Melanin Synthesis by Mycelial Culture Broth of Paecilomyces japonica in the Mulberry

Cited by 8 publications

References 5 publications

Antioxidative Activity and Chemical Characteristics of Cordycepin-enriched Cordyceps militaris JLM0636 Powder

Antioxidative Activity and Chemical Characteristics of Cordycepin-enriched Cordyceps militaris JLM0636 Powder

Antioxidant and Anti-Inflammatory Activity and Cytotoxicity of Ethanol Extracts from Rhynchosia nulubilis Cultivated with Ganoderma lucidum Mycelium

Trends in the Efficacy and Safety of Ingredients in Acne Skin Treatments

Contact Info

Product

Resources

About