NHE1 Protein in Repetitive Mild TBI-Mediated Neuroinflammation and Neurological Function Impairment
John Paul Bielanin,
Shamseldin Ayman Hassan Metwally,
Helena C.M. Oft
et al.
Abstract:Mild traumatic brain injuries (mTBIs) are highly prevalent and can lead to chronic behavioral and cognitive deficits, often associated with the development of neurodegenerative diseases. The formation of reactive oxygen species (ROS) and oxidative stress have been implicated in mTBI-mediated axonal injury and pathogenesis. However, the underlying mechanisms and contributing factors are not completely understood. In this study, utilizing a murine model of repetitive mTBI (r-mTBI) involving five closed-skull con… Show more
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