Next-Generation Sequencing: A Promising Tool for Vaccines and Other Biological Products

Nellimarla, Srinivas; Kesanakurti, Prasad

doi:10.3390/vaccines11030527

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2024

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Cited by 2 publications

References 13 publications

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Ecology and environmental omics

Kesheri,

Kanchan,

Srivastava

et al. 2024

Integrative Omics

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Ecology and environmental omics

Kesheri,

Kanchan,

Srivastava

et al. 2024

Integrative Omics

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Recent advances on vaccines against malaria: A review

Malik,

Waheed

2024

Asian Pacific Journal of Tropical Medicine

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This review aims to summarize the currently viable vaccine strategies including the approved vaccines and the those in trials for next-generation malaria vaccines. Data on malaria vaccine development was collected through a comprehensive review. The literature search was performed using databases including Google Scholar, PubMed, NIH, and Web of Science. Various novel approaches of vaccination are being developed, including those based on radiation-attenuated strategies, monoclonal antibodies, targeted immunogenic peptides, RNA and DNA vaccines, nanoparticle-based vaccines, protein-based vaccination protocols, and whole organism-based vaccination strategies. Trials on RTS, S have entered phase III testing, and those based on blood-stage vaccines and vaccines to interrupt malarial transmission have advanced to higher stages of trials. Mathematical modeling, combined drug and vaccine strategies, mass drug administration, polyvalent vaccine formulations, and targeted vaccination campaigns is playing an important role in malarial prevention. Furthermore, assessing coverage, accessibility, acceptability, deployment, compilation, and adherence to specific vaccination strategies in endemic regions is essential for vaccination drives against malaria.

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Next-Generation Sequencing: A Promising Tool for Vaccines and Other Biological Products

Abstract: Next-generation sequencing (NGS), also known as high-throughput sequencing (HTS), is a commonly used term to represent a set of DNA sequencing technologies that have been in use for almost two decades [...]

Cited by 2 publications

References 13 publications

Ecology and environmental omics

Ecology and environmental omics

Recent advances on vaccines against malaria: A review

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