Next-Generation Healthcare: Enabling Technologies for Emerging Bioelectromagnetics Applications

Kiourti, Asimina; Abbosh, Amin; Αθανασίου, Μαρία; Björninen, Toni; Eid, Aline; Furse, Cynthia; Ito, Koichi; Lazzi, Gianluca; Manoufali, Mohamed; Pastorino, Matteo; Tentzeris, Manos M.; Tisdale, Katrina; Topsakal, Erdem; Ukkonen, Leena; Whittow, William G.; Zhang, Huanan; Nikita, Konstantina S.

doi:10.1109/ojap.2022.3162110

Cited by 40 publications

(15 citation statements)

References 298 publications

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“…One of the key points in chronic and old-age diseases is remote and safe monitoring of patient status and physiological parameters (e.g., temperature, heartbeat, and breath), without affecting their everyday life. In this respect, localization and tracking are of high interest, and several innovative electromagnetic systems and techniques have been proposed in literature [188], [189], [190].…”

Section: Innovative Electromagnetic Systems For Healthcare and Assist...mentioning

confidence: 99%

The Next Generation of eHealth: A Multidisciplinary Survey

et al. 2022

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Over the past two years, the spread of COVID-19 has spurred the use of information and communication technologies (ICT) in aid of healthcare. The need to guarantee continuity to care has promoted research and industry activities aimed at developing solutions for the digitalization of the procedures to be performed to provide health services, even in emergency scenarios. Digital collection, transmission, and processing of health data represent the starting point for fulfilling this innovation process but also bring heterogeneous challenges. These motivations led to the elaboration of this work, which analyzes innovative and technological tools for the development of digital health (eHealth) through the collection of multisectoral literature, produced thanks to the cooperation of varied research groups, thus providing a multidisciplinary survey. Since digital health is expected to be one of the leading applications of the sixth-generation (6G) wireless cellular networks, this paper covers the related telecommunications aspects. Furthermore, the exploitation of artificial intelligence paradigms to elaborate massive amounts of biological data is examined. Given the extreme sensitivity of health data, this paper also investigates security and privacy issues. In particular, the main techniques and approaches to guarantee security properties (i.e., anonymity, responsibility, authentication, confidentiality, integrity, non-repudiation, and revocability) are studied. Applications involving innovative electromagnetic systems for healthcare and assisted living services are described to provide an example of an eHealth scenario leveraging ICT. Finally, the telemedicine-related regulations of the European Commission are analyzed, with particular reference to the General Data Protection Regulation (GDPR).

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Section: Innovative Electromagnetic Systems For Healthcare and Assist...mentioning

confidence: 99%

The Next Generation of eHealth: A Multidisciplinary Survey

et al. 2022

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“…Among the many biomedical applications of microwave (MW) diagnostic imaging [47]- [49], its use in the framework of thermal therapy looks promising, due to its capability of being a non-invasive, cost effective, fast and reliable strategy [50]- [52]. In particular, MW imaging is an approach under investigation for tissues temperature monitoring during hyperthermia [53] and ablation [54].…”

Section: Introductionmentioning

confidence: 99%

Feasibility Analysis of Theranostic Magnetic Scaffolds for Microwave Monitoring of Hyperthermia Treatment of Bone Tumors

Lodi¹,

Curreli²,

Dachena³

et al. 2023

Preprint

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<p>Magnetic biomaterials are multifunctional tools currently under investigation as theranostic platforms for biomedical applications. They can be implanted in bone tissue after bone cancer resection to perform local interstitial hyperthermia treatment. Given the requirements of high quality treatment, the hyperthermia therapy should be performed monitoring the system temperature, to avoid hot spots and control the treatment outcome. It is known that the magnetic properties of such implants vary with temperature. It is hypotesized that the treatment dynamic could be monitored using a microwave monitoring system. The variation of the electromagnetic properties of the biological tissues and the magnetic implant during the therapy would result in a different propagation of the microwave signal. This work investigates the feasibility of using microwaves to non-invasively monitor hyperthermia treatments with a simplified monodimensional propagation model. The forward problem is solved to identify the working frequencies, the matching medium properties and study several candidate materials. By using the numerical solutions from nonlinear and multiphysics simulations of the bone tumor hyperthermia treatment using magnetic scaffolds, the microwave signal propagation dynamic is studied. From our feasibility analysis, we found that it is possible to correlate the average tumor temperature with significant (~20 dB) variations in the transmission coefficient during a typical interstitial hyperthermia session using magnetic scaffolds. Our work brings together, for the first time, the electromagnetic material properties, the physio-pathology and physics of the hyperthermia treatment and the microwave propagation problem, thus paving the route for the development of an innovative theranostic system.</p>

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“…In this context, microwave imaging (MWI) is a technology owing to short acquisition times, easy and safe deployment, cost-effectiveness, and portability, which enables bedside use and continuous follow-up [3], [4], relying on the perturbation of an excited electromagnetic (EM) field caused by the temporal variation of different dielectric properties of the stroke-affected tissue. Thus, MWI has potential significance for clinical practice since it can provide fast and continuous image outcomes with relevant information, albeit limited in resolution in comparison to MRI and CT.…”

Section: Introductionmentioning

confidence: 99%

Experimental Assessment of Real-Time Brain Stroke Monitoring via a Microwave Imaging Scanner

Rodriguez-Duarte

Origlia

Vasquez

et al. 2022

IEEE Open J. Antennas Propag.

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This paper presents the experimental validation of a microwave imaging system for real-time monitoring of brain stroke in the post-acute stage. The system exploits a low-complexity sensing apparatus and a multi-frequency microwave imaging algorithm with a novel artifact removal feature. Phantoms of a homogeneous anthropomorphic head and an ellipsoidal non-static stroke mimicking target, varying gradually from 0 cm 3 to 60 cm 3 , are employed for the experiments. The phantom and the evolving target are filled with appropriate alcohol-based mixtures to mimic the different dielectric properties of the relevant tissue. The microwave imaging scanner operates using a 22-antennas architecture formed by printed flexible antennas with a custom-made matching medium. The system provides 3-D images of the entire brain region, exploiting differential multi-view scattering measures and the distorted Born approximation to build a precomputed imaging kernel. The results show the system's capability to follow up the continuous progression of hemorrhage and ischemia zones with centimetric spatial resolution and to provide information on whether the stroke is growing or shrinking.

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Next-Generation Healthcare: Enabling Technologies for Emerging Bioelectromagnetics Applications

Cited by 40 publications

References 298 publications

The Next Generation of eHealth: A Multidisciplinary Survey

The Next Generation of eHealth: A Multidisciplinary Survey

Feasibility Analysis of Theranostic Magnetic Scaffolds for Microwave Monitoring of Hyperthermia Treatment of Bone Tumors

Experimental Assessment of Real-Time Brain Stroke Monitoring via a Microwave Imaging Scanner

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