2010
DOI: 10.1002/ajpa.21376
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News from the west: Ancient DNA from a French megalithic burial chamber

Abstract: Recent paleogenetic studies have confirmed that the spread of the Neolithic across Europe was neither genetically nor geographically uniform. To extend existing knowledge of the mitochondrial European Neolithic gene pool, we examined six samples of human skeletal material from a French megalithic long mound (c.4200 cal BC). We retrieved HVR-I sequences from three individuals and demonstrated that in the Neolithic period the mtDNA haplogroup N1a, previously only known in central Europe, was as widely distribute… Show more

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Cited by 42 publications
(49 citation statements)
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References 45 publications
(67 reference statements)
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“…On the contrary, similarly to southern Europe Neolithic specimens (4), there is no evidence in the Treilles samples of the N1a haplogroup, which was highly present in central Europe and Atlantic coast Neolithic cultures (6,8). According to mitochondrial data, the Neolithic wave in the Treilles genetic pool is thus more likely to be Mediterranean than central European in origin.…”
Section: Resultsmentioning
confidence: 87%
See 1 more Smart Citation
“…On the contrary, similarly to southern Europe Neolithic specimens (4), there is no evidence in the Treilles samples of the N1a haplogroup, which was highly present in central Europe and Atlantic coast Neolithic cultures (6,8). According to mitochondrial data, the Neolithic wave in the Treilles genetic pool is thus more likely to be Mediterranean than central European in origin.…”
Section: Resultsmentioning
confidence: 87%
“…In this context, molecular analyzes of ancient human populations of the end of the Neolithic are crucial to understand the origin and genetic structure of the European population. Because DNA is a very fragile molecule, rarely well preserved in ancient European specimens, only few molecular analyzes have been carried out on Neolithic remains, and they have often been limited to the study of mtDNA (4)(5)(6)(7)(8)(9). The few published studies on nuclear DNA concern a small number of individuals (10)(11)(12)(13).…”
mentioning
confidence: 99%
“…The procedures were performed in the aDNA facilities of the laboratory of Past and Present Populations Anthropology (Université de Bordeaux, UMR PACEA) in a laboratory dedicated to aDNA analysis, as described in [21].…”
Section: (B) Dna Extractionmentioning
confidence: 99%
“…N1a dates to approximately 20 kya and is a relatively rare haplogroup in Europe, reaching higher frequencies in Eastern Africa and in the Arabian Peninsula. 54 Although this haplogroup was found in Neolithic and Mesolithic skeletal remains from Central and Northwest Europe, [55][56][57] it was absent in previous studies on Iberian Neolithic populations, suggesting a rather uneven genetic and geographical spread of this lineage across Europe. 58,59 However, more recently, Gamba et al 60 detected this lineage in Neolithic northeast Iberia, evidencing a possible scenario of several Neolithic colonization events along the Mediterranean, from the Near East.…”
Section: Echoes From Sepharad I Nogueiro Et Almentioning
confidence: 99%