Newly synthesized dihydroquinazoline derivative from the aspect of combined spectroscopic and computational study

Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography

“…Moreover, quinazolinones, such as quinazolin-2,4-diones, and their corresponding 2-thioxo-quinazolin-4-ones undergo several biological activities, such as carbonic anhydrase [28][29][30][31], COX-1/2 [32,33], tyrosine kinase inhibitions [34], and antitumor activity [35][36][37][38][39][40][41]. Due to the biological importance of quinazolin-2,4-diones and 2-thioxo-quinazolin-4-ones, their molecular structures are studied by spectroscopic and theoretical methods [42][43][44][45][46]. Moreover, urea molecule, which constitutes quinazolin-2,4dione, was extensively studied experimentally and theoretically [47][48][49][50][51][52][53][54][55].…”