2022
DOI: 10.14218/jcth.2021.00553
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Newcastle Disease Virus/HK84: Next Potential Star for Targeted Immunotherapy of Hepatocellular Carcinoma?

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“…NDV-HK84 is a wild-type OV. A study found that NDV-HK84 could inhibit tumor growth and had an oncolytic effect by activating IFN signaling in vitro and in vivo HCC models [93 , 94] . The applications of genetically engineered NDV in HCC treatment have been investigated for years.…”
Section: Ov-based Hcc Treatmentmentioning
confidence: 99%
“…NDV-HK84 is a wild-type OV. A study found that NDV-HK84 could inhibit tumor growth and had an oncolytic effect by activating IFN signaling in vitro and in vivo HCC models [93 , 94] . The applications of genetically engineered NDV in HCC treatment have been investigated for years.…”
Section: Ov-based Hcc Treatmentmentioning
confidence: 99%