Newborn Circumcision

Brady, Michael T.

doi:10.1001/archpediatrics.2009.248

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Cited by 3 publications

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“…Genital ulcer disease was also reduced among males and their female partners. In addition, male circumcision reduces urinary tract infection, reduces penile cancer and reduces hygiene-related conditions (phimosis, paraphimosis and balanitis) 108 . The underlying mechanism for such enhanced protection in circumcised men is unknown, but could be related to the absence of the type II mucosal surface.…”

Section: Figurementioning

confidence: 99%

Antiviral immune responses in the genital tract: clues for vaccines

2010

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Mucosal surfaces are often exploited as a portal of entry by a wide variety of microorganisms. An advanced understanding has been gained over the past decade of the immune system of the gastrointestinal and the respiratory mucosae. However, despite the fact that many viruses are transmitted sexually through the genital tract, the immune system of the male and female genital mucosae has received much less attention. Here, I describe and highlight differences of the innate and adaptive immune systems of the genital and intestinal mucosae, and discuss the challenges we face in the development of successful vaccines against sexually transmitted viral pathogens.

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Section: Figurementioning

confidence: 99%