New μs-pulsed DC glow discharge assembly on a fast flow high power source for time resolved analysis in high resolution mass spectrometry

Churchill, G. G.; Putyera, Karol; Weinstein, Viktoria; Wang, Xinwei; Steers, Edward B. M.

doi:10.1039/c1ja10086f

Cited by 12 publications

(4 citation statements)

References 23 publications

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“…18 FPGAs have found several applications in the development of analytical instrumentation, including: fast data acquisition, frequency counting, multiplexing, filtering, processing, control of auxiliary devices ( pumps, valves, heaters, lasers, LEDs), synchronisation, interfacing with computers, recording, data storage, data transfer, peak analysis, feedback regulation, timing and signal generation (Table S1 †). They have been used to build a variety of analytical instruments, including electrochemical sensors, [19][20][21][22] quartz crystal microbalances, [23][24][25][26][27] cell sorters, [28][29][30][31][32] mass spectrometry systems, [33][34][35][36][37][38][39] and nuclear magnetic resonance spectrometers. [40][41][42][43] While there is a growing interest in miniaturisation of NMR spectrometers, 44,45 FPGAs help to solve the engineering problems associated with the electronic circuitry to support the operation of such systems.…”

Section: Hardwarementioning

confidence: 99%

Universal electronics for miniature and automated chemical assays

Urban

2015

Analyst

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This minireview discusses universal electronic modules (generic programmable units) and their use by analytical chemists to construct inexpensive, miniature or automated devices. Recently, open-source platforms have gained considerable popularity among tech-savvy chemists because their implementation often does not require expert knowledge and investment of funds. Thus, chemistry students and researchers can easily start implementing them after a few hours of reading tutorials and trial-and-error. Single-board microcontrollers and micro-computers such as Arduino, Teensy, Raspberry Pi or BeagleBone enable collecting experimental data with high precision as well as efficient control of electric potentials and actuation of mechanical systems. They are readily programmed using high-level languages, such as C, C++, JavaScript or Python. They can also be coupled with mobile consumer electronics, including smartphones as well as teleinformatic networks. More demanding analytical tasks require fast signal processing. Field-programmable gate arrays enable efficient and inexpensive prototyping of high-performance analytical platforms, thus becoming increasingly popular among analytical chemists. This minireview discusses the advantages and drawbacks of universal electronic modules, considering their application in prototyping and manufacture of intelligent analytical instrumentation.

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Section: Hardwarementioning

confidence: 99%

Universal electronics for miniature and automated chemical assays

Urban

2015

Analyst

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“…A slightly different approach was established by Churchill et al 137 Finally, Thermo Fischer Scientific adapted this system and introduced their own version with limited capabilities (fixed pulse frequency) in their instrument.…”

Section: Depth Profiling By Gdmsmentioning

confidence: 99%

Glow Discharge Mass Spectrometry

Venzago

Pisonero

2014

Sector Field Mass Spectrometry for Elemental and Isotopic Analysis

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GDMS is based on a glow discharge ion source, which generates ions through sputtering (cathodic sputtering) of a solid surface and ionisation (electron impact or Penning ionisation) by a glow discharge plasma. A glow discharge plasma is formed by the passage of an electric current through a low-pressure gas. The ions are separated in a mass spectrometer and finally recorded at a detector. GDMS is a method for the direct determination of trace elements in solid states providing traceelement information of solid samples. Beside the direct current (DC) mode, analytical glow discharges can also be operated in a radiofrequency (RF) mode, most often applied for analysis of nonconducting samples (Figures 13.1 and 13.2).

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“…It was stated that the resolving power was only limited by the mass spectrometer and not by this thirdgeneration array detector. 180 Churchill et al developed a new microsecond-pulsed dc GD assembly on a fast flow high power source for time-resolved analysis with a high-resolution MS. 181 This new assembly allowed submicrometer layer analysis for depth profiling of thin layered structures, such as photovoltaic films. For GD-OES, Wagatsuma and Urushibata reported on a fast Fourier transform (FFT) analyzer to estimate the emission intensity from an rf GD.…”

Section: ■ Atomic Emission Spectrometrymentioning

confidence: 99%