New Type of Skipped Oligoaziridines: Synthesis of New Fatty AcidDerivatives Containing Aziridine Functions

New Syntheses with Oils and Fats as Renewable Raw Materials for the Chemical Industry

“…[26,27] Scheme 3. [27] The aziridines 22 and the episulfides 23, [28] the latter being accessible from the epoxides 14 b and 15 b (Scheme 4), are interesting intermediates in the synthesis of heterocyclic and highly functionalized fatty compounds. [26] Methyl di-and triepiminooctadecanoates 22 b and 22 c can be synthesized in a similar manner from the methyl di-and triepoxyoctadecanoates 15 b and 16 b.…”

Unprotected Aziridines: A Synthetic Overview

“…Aziridines that contain fatty acids have demonstrated promising biological properties and are good candidates for further functionalization; consequently, several groups have reported the synthesis of fatty‐acid‐derived aziridines –. Jurgen O. Metzger and Sandra Fürmeier synthesized bis‐ and tris‐aziridines from long‐chain unsaturated fatty acids, such as linoleic and linolenic acid . Initially, they tried previously reported approaches, as shown in Scheme a, but the first two methods were unsuccessful.…”

Neue Synthesen mit Ölen und Fetten als nachwachsende Rohstoffe für die chemische Industrie

“…[26,27] Die Aziridine 22 und ebenso die aus den Epoxiden 14 b und 15 b zugänglichen Episulfide 23 [28] (Schema 4) sind interessante Zwischenstufen zur Synthese heterocyclischer und hochfunktionalisierter Fettstoffe. [27] Schema 4. Synthese von Epiminooctadecansäuremethylester 22 a aus Epoxyoctadecansäuremethylester 14 b: a) NaN 3 , NH 4 Cl, EtOH, H 2 O; b) Ph 3 P, THF.…”