“…Rhenium(I) tricarbonyl complexes not only have application as models for similar technetium(I) complexes in radiopharmacy, but their anticancer and antimicrobial properties have recently been investigated by several research groups, including ours (Gantsho et al, 2020;Collery et al, 2019;Li et al, 2012;Otero et al, 2019;Leonidova & Gasser, 2014;Brink et al, 2018;Sovari et al, 2020Sovari et al, , 2021Varma et al, 2020). Similarly, the bidentate ligand tropolone and its derivatives have shown anticancer and antiviral properties on their own (Ishihara et al, 2010;Borowski et al, 2007;Dittes et al, 1995a) and when combined with metal complexes (Ishihara et al, 2010;Borowski et al, 2007;Dittes et al, 1995a,b;Trust, 1975). Kinetic studies have shown that tropolone and other O,O 0bidentate ligands like 3-hydroxyflavone increase the rate of substitution of water or methanol in fac-[Re(Bid)X(CO) 3 ] n (Bid = bidentate ligand, X = H 2 O or methanol, and n = 0 or 1+) type complexes by up to 20000 times (Gantsho et al, 2020;Schutte et al, 2012;Schutte-Smith et al, 2019b;Schutte et al, 2011;Manicum et al, 2020;Schutte-Smith & Visser, 2015).…”