New triterpenoids from the roots of Rhododendron molle as positive modulators of GABAA receptors

Zhang, Huanping; Zhu, Yuxun; Zhang, Zhao-Xin; Chai, Li-Sha; Liu, Yun‐Bao; Yu, Haibo; Li, Yong

doi:10.1016/j.tet.2020.131455

Tetrahedron

2020

DOI: 10.1016/j.tet.2020.131455

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New triterpenoids from the roots of Rhododendron molle as positive modulators of GABAA receptors

Huanping Zhang

Yuxun Zhu

Zhao-Xin Zhang

et al.

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“…Moreover, previous studies suggested that different organs and tissues of R. molle (including flower and root, etc.) could be used as analgesics and insecticides (Zhong et al 2006;Li et al 2020;Zhang et al 2020). Due to lacking genome information and available molecular markers, the phylogenetic relationship of R. molle with other related species is still unclear.…”

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The complete chloroplast genome of Rhododendron molle and its phylogenetic position within Ericaceae

Liu

et al. 2021

Mitochondrial DNA Part B

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Rhododendron mole (Blume) G. Don is an attractive ornamental and valuable medicinal plant which widely distributed in the southern regions of China. In order to promote the studies on the genetic diversity of this species, we assembled the complete chloroplast (cp) genome of R. molle by using the genome skimming approach. The results showed that the cp genome of R. molle exhibited a quadripartite cycle with 197,877 bp, comprising of two inverted repeats (IRs) of 43,831 bp separated by a large single copy (LSC) region of 110,189 bp and a quite small single copy (SSC) region of 26 bp. It encodes 146 genes, including 92 protein-coding, 46 tRNA, and eight rRNA genes. The overall GC content of the cp genome was 36.0%. The phylogenetic analysis indicated that R. molle is closely related to R. delavayi. Thus, the cp genome sequence of R. molle provides a rich source of genetic information for studies on Rhododendron taxonomy, phylogeny, and evolution, as well as lays the foundation for further development and utilization of R. molle.

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confidence: 99%

The complete chloroplast genome of Rhododendron molle and its phylogenetic position within Ericaceae

Liu

et al. 2021

Mitochondrial DNA Part B

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Review of natural plant-derived seco-triterpenoids and derived saponins from 2020 to 2023: new compounds, distributions, diverse activities and structure–activity relationships

Wei,

Wang,

Liu

et al. 2024

Phytochem Rev

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Structurally diverse analgesic diterpenoids from the flowers of Rhododendron molle

Zheng,

Huang,

Feng

et al. 2024

Fitoterapia

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New triterpenoids from the roots of Rhododendron molle as positive modulators of GABAA receptors

Cited by 5 publications

References 25 publications

The complete chloroplast genome of Rhododendron molle and its phylogenetic position within Ericaceae

The complete chloroplast genome of Rhododendron molle and its phylogenetic position within Ericaceae

Review of natural plant-derived seco-triterpenoids and derived saponins from 2020 to 2023: new compounds, distributions, diverse activities and structure–activity relationships

Structurally diverse analgesic diterpenoids from the flowers of Rhododendron molle

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