New Trends on Optical Fiber Tweezers

Ribeiro, R. S. Rodrigues; Soppera, Olivier; Oliva, Abel; Guerreiro, A.; Jorge, P. A. S.

doi:10.1109/jlt.2015.2448119

Cited by 71 publications

(14 citation statements)

References 65 publications

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“…Also optical fibres have been used to replace standard cw lasers in optical manipulation experiments. Strong intensity gradients have been obtained at the tips of optical fibres by micro-machining them with techniques typical of material science, such as chemical etching, photo-polymerization and polishing [125], which permit to realize increasingly complex configurations of fibrebased trapping. Anyway, the most attractive property of this approach is its capability of performing optical manipulations without the need for external bulk optical elements, which represents a first step towards the integration of optical tweezers with Lab-on-a-chip (LOC) functionalities.…”

Section: Discussionmentioning

confidence: 99%

Optical tweezers in single-molecule experiments

et al. 2020

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In the last decades, optical tweezers have progressively emerged as a unique tool to investigate the biophysical world, allowing to manipulate and control forces and movements of one molecule at a time with unprecedented resolution. In this review, we present the use of optical tweezers to perform single-molecule force spectroscopy investigations from an experimental perspective. After a comparison with other single-molecule force spectroscopy techniques, we illustrate at an introductory level the physical principles underlying optical trapping and the main experimental configurations employed nowadays in single-molecule experiments. We conclude with a brief summary of some remarkable results achieved with this approach in different biological systems, with the aim to highlight the great variety of experimental possibilities offered by optical tweezers to scientists interested in this research field.

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Section: Discussionmentioning

confidence: 99%

Optical tweezers in single-molecule experiments

et al. 2020

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“…This is caused by the increase in the solution refractive index to 1.32, resulting in a reduced contrast and lower focusing power. The optical forces acting on the PMMA particles are calculated based on the Lorentz model, considering the beads composed by dipoles 15, 47 . Thus, the force is given by:where ε 0 is the vacuum permittivity, ε p is the particle relative permittivity, ε m is the relative permittivity of the surrounding media and I is the electric field intensity.…”

Section: Discussionmentioning

confidence: 99%

“…With this in mind, this paper presents a set of Fresnel zone and phase plates, fabricated on common optical fibres using focused ion beam milling for trapping purposes. The literature on trapping using single optical fibres has seen advances in the design and capabilities of the lenses 15 . Early on, optical fibre probes were limited to tapered fibres 16 , fabricated by chemical etching 17 , thermal processes 18 , among others 19 .…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells

Ribeiro

Dahal²,

Guerreiro

et al. 2017

Sci Rep

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The development of economical optical devices with a reduced footprint foreseeing manipulation, sorting and detection of single cells and other micro particles have been encouraged by cellular biology requirements. Nonetheless, researchers are still ambitious for advances in this field. This paper presents Fresnel zone and phase plates fabricated on mode expanded optical fibres for optical trapping. The diffractive structures were fabricated using focused ion beam milling. The zone plates presented in this work have focal distance of ~5 µm, while the focal distance of the phase plates is ~10 µm. The phase plates are implemented in an optical trapping configuration, and 2D manipulation and detection of 8 µm PMMA beads and yeast cells is reported. This enables new applications for optical trapping setups based on diffractive optical elements on optical fibre tips, where feedback systems can be integrated to automatically detect, manipulate and sort cells.

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“…In addition, OFTs make optical manipulation a low cost technique due to the easy fabrication procedures. OFTs can also be integrated into small devices, such as optofluidic channels and chips [17]. OFTs were first presented in 1993, where two aligned singlemode optical fibers were used for optical trapping [18].…”

Section: Introductionmentioning

confidence: 99%

Optical Fiber Tweezers: A Versatile Tool for Optical Trapping and Manipulation

Zhao

Shi

et al. 2020

Micromachines

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Optical trapping is widely used in different areas, ranging from biomedical applications, to physics and material sciences. In recent years, optical fiber tweezers have attracted significant attention in the field of optical trapping due to their flexible manipulation, compact structure, and easy fabrication. As a versatile tool for optical trapping and manipulation, optical fiber tweezers can be used to trap, manipulate, arrange, and assemble tiny objects. Here, we review the optical fiber tweezers-based trapping and manipulation, including dual fiber tweezers for trapping and manipulation, single fiber tweezers for trapping and single cell analysis, optical fiber tweezers for cell assembly, structured optical fiber for enhanced trapping and manipulation, subwavelength optical fiber wire for evanescent fields-based trapping and delivery, and photothermal trapping, assembly, and manipulation.

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New Trends on Optical Fiber Tweezers

Cited by 71 publications

References 65 publications

Optical tweezers in single-molecule experiments

Optical tweezers in single-molecule experiments

Fabrication of Fresnel plates on optical fibres by FIB milling for optical trapping, manipulation and detection of single cells

Optical Fiber Tweezers: A Versatile Tool for Optical Trapping and Manipulation

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