New topical photodynamic therapy for management of primary axillary hyperhidrosis

Salah, Manal; Attia, Abeer T

doi:10.1097/01.ewx.0000392816.83337.a4

Cited by 6 publications

(15 citation statements)

References 24 publications

(34 reference statements)

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“…Salah and Attia showed durable results of PDT for axillary hyperhidrosis up to 8 months after the last treatment session. 9 Thus, the treatment stability of PDT is comparable to other popular treatment lines like botulinum toxin injections which produce effects that are maintained for a minimum of 3-4 months. 6 Photodynamic therapy showed high tolerability and side effects were mild and transient.…”

Section: Discussionmentioning

confidence: 94%

“…Hence, new treatments are arguably searched to meet the patient's needs and expectations 6 . PDT was tried in eccrine gland disorders and proved a good efficacy in axially hyperhidrosis 9 …”

Section: Discussionmentioning

confidence: 99%

“…Since PDT is frequently used as a nonclinic procedure via daylight‐mediated PDT, 7 this option could be considered for palmar hyperhidrosis. Another drawback was the adoption of a relatively long incubation time in the current study based on implementation of longer incubation times for topical PDT for axillary hyperhidrosis, and because of the increased skin thickness in palms compared with axillae 9,15 . Implementation of various incubation times to determine precisely the time needed for an adequate absorption of different photosensitizers through the palmar skin to reach a sufficient concentration in the target organ may result in reduction of the needed incubation time and thus better patient's satisfaction.…”

Section: Discussionmentioning

confidence: 99%

“…9,15 Implementation of various incubation times to determine precisely the time needed for an adequate absorption of different photosensitizers through the palmar skin to reach a sufficientT A B L E 2…”

mentioning

confidence: 99%

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Efficacy of photodynamic therapy for treatment of primary palmar hyperhidrosis

Shabaik

Shaheen

Soltan

2020

Dermatologic Therapy

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Palmar hyperhidrosis represents a condition with a significant cosmetic and psychological burden. Various treatment modalities are available; however, searching for newer options to meet patients' needs and expectations is encouraged. The study aimed to evaluate the efficacy of photodynamic therapy (PDT) for treatment of primary palmar hyperhidrosis. Two different photosensitizers for PDT were evaluated: eosin Y, and methylene blue. The study focused on the clinical efficacy, patient's satisfaction, and the time and number of sessions needed to achieve a satisfactory response. Twenty patients with primary palmar hyperhidrosis were enrolled in a single‐center clinical study. Patients were treated with PDT for a maximum of eight sessions. Two photosensitizers were tested: eosin Y, and methylene blue for the right and left hand, respectively. The Hyperhidrosis disease severity scale (HDSS), and Sweating Intensity Visual Scale of Minor's test were used for assessment. Photodynamic therapy effectively reduced the severity scores of hyperhidrosis with comparable results between the two photosensitizers. The treatment effect was maintained up to 3 months after the last procedure. Photodynamic therapy is a good treatment option for primary palmar hyperhidrosis with results maintainable for 3 months after the treatment end.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Efficacy of photodynamic therapy for treatment of primary palmar hyperhidrosis

Shabaik

Shaheen

Soltan

2020

Dermatologic Therapy

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“…Sin embargo, se requieren más estudios para poder recomendarla como terapia. 29 conclusiones Dado que la hiperhidrosis afecta profundamente la calidad de vida de los pacientes, es fundamental conocer las alternativas terapéuticas disponibles en la actualidad, considerando los posibles beneficios y efectos adversos de cada opción.…”

Section: E Terapia Fotodinámicaunclassified

Manejo médico de la hiperhidrosis

Lorca

Bruning²,

Giordano³

et al. 2018

Rev. chil. dermatol

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La hiperhidrosis es un aumento patológico de la sudoración, que puede asociarse a patologías médicas y fármacos, afectando en forma significativa la calidad de vida. La hiperhidrosis focal primaria es una patología común, cuyo manejo es un desafío. Están disponibles múltiples terapias para el tratamiento de hiperhidrosis, incluyendo productos tópicos, iontoforesis, toxina botulínica, fármacos sistémicos, cirugía y nuevos equipos para destrucción selectiva de las glándulas sudoríparas. El propósito de este artículo es revisar la literatura, enfocándose en las terapias no quirúrgicas y opciones de tratamiento emergentes.

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Hyperhidrosis—aetiopathogenesis, diagnosis, clinical symptoms and treatment

Wohlrab

Kreft

2018

Hautarzt

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Although primary hyperhidrosis is a common disease, secondary symptomatic hyperhidrosis is rather rare. Primary hyperhidrosis is a complex neuropathic dysregulation with a genetic predisposition and is diagnosed when patients show pathologic sweating patterns and excessive sweating for at least 6 months and fulfill at least four of the following criteria: affected areas are axillae and/or palms and/or soles and/or forehead; symmetry; no night sweating; at least once a week; onset before the age of 25; positive family history; negative impact on daily activities. Frequently used therapies are topical aluminum salts and anticholinergics, iontophoresis in water, and intracutaneous botulinum toxin. Anticholinergics are also used as systemic treatment. Surgical procedures are used as a last result. Furthermore procedures using thermolysis have been developed.

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New topical photodynamic therapy for management of primary axillary hyperhidrosis

Cited by 6 publications

References 24 publications

Efficacy of photodynamic therapy for treatment of primary palmar hyperhidrosis

Efficacy of photodynamic therapy for treatment of primary palmar hyperhidrosis

Manejo médico de la hiperhidrosis

Hyperhidrosis—aetiopathogenesis, diagnosis, clinical symptoms and treatment

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