2021
DOI: 10.3390/ijerph18136985
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New Tools to Support the Risk Assessment Process of Nanomaterials in the Insurance Sector

Abstract: During the last decade, the use of nanomaterials, due to their multiple utilities, has exponentially increased. Nanomaterials have unique properties such as a larger specific surface area and surface activity, which may result in health and environmental hazards different from those demonstrated by the same materials in bulk form. Besides, due to their small size, they can easily penetrate through the environmental and biological barriers. In terms of exposure potential, the vast majority of studies are focuse… Show more

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Cited by 4 publications
(2 citation statements)
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References 22 publications
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“…Case-by-case determination of exposure and hazard data for each application and individual NM variant is not possible due to the time and cost required, as well as the ethical challenges inherent in animal experimentation, and thus there is a strong motivation to develop in silico models that can predict human exposure to, and impacts of, NMs based on a reduced set of input parameters, as part of an integrated approach to testing and assessment (IATA). An example of the use of computational tools in the context of risk assessment was introduced by Mollá et al , 1 who recently proposed NanoSerpa, an application for the risk assessment of NMs in the insurance sector, which was developed by integrating hazard-related data and optimized exposure models. The focus of NanoSerpa is on estimation of the insurance liability arising from accidental NMs spills during production, transport or use of NMs-containing products, based on input data regarding the type of NM and the accident scenario, utilising probabilistic models to predict emission, health hazard values and risk indices.…”
Section: Introductionmentioning
confidence: 99%
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“…Case-by-case determination of exposure and hazard data for each application and individual NM variant is not possible due to the time and cost required, as well as the ethical challenges inherent in animal experimentation, and thus there is a strong motivation to develop in silico models that can predict human exposure to, and impacts of, NMs based on a reduced set of input parameters, as part of an integrated approach to testing and assessment (IATA). An example of the use of computational tools in the context of risk assessment was introduced by Mollá et al , 1 who recently proposed NanoSerpa, an application for the risk assessment of NMs in the insurance sector, which was developed by integrating hazard-related data and optimized exposure models. The focus of NanoSerpa is on estimation of the insurance liability arising from accidental NMs spills during production, transport or use of NMs-containing products, based on input data regarding the type of NM and the accident scenario, utilising probabilistic models to predict emission, health hazard values and risk indices.…”
Section: Introductionmentioning
confidence: 99%
“…The focus of NanoSerpa is on estimation of the insurance liability arising from accidental NMs spills during production, transport or use of NMs-containing products, based on input data regarding the type of NM and the accident scenario, utilising probabilistic models to predict emission, health hazard values and risk indices. 1 Other tools for risk assessment of NMs are also emerging, including hazard classification tools, 2–4 screening level models for predicting NMs transport and concentrations in the environment such as SimpleBox4Nano, 5,6 and probabilistic models of NMs flows 7,8 from production to waste treatment. However, the various models have yet to be made inter-operable and combined into an overall IATA in order to facilitate complete ( in silico ) risk assessment.…”
Section: Introductionmentioning
confidence: 99%