New thoughts on first seizure

McCorry, Dougall; Cavanna, Andrea E.

doi:10.7861/clinmedicine.10-4-395

Cited by 10 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients who have more than two seizures in 12 h have progressively smaller elevations, presumably because stored PRL from the pituitary lactotrophs is exhausted. [ 7 11 12 ]…”

Section: Discussionmentioning

confidence: 99%

Role of Biomarkers in Differentiating New-onset Seizures from Psychogenic Nonepileptic Seizures

Javali

Acharya

Shah

et al. 2017

Journal of Neurosciences in Rural Practice

View full text Add to dashboard Cite

Introduction:Review of literature revealed very limited studies considering a combination of serum prolactin (PRL) and serum creatine kinase (CK) as markers for differentiating epileptic and psychogenic nonepileptic seizures (PNES). Therefore, in the present study, we analyzed the role of serum PRL and serum CK, individually and in combination.Methodology:This prospective study was conducted in a tertiary care medical teaching hospital over a period of 18 months. Patients aged over 15 years suspected to have new-onset seizures presenting within 5 h of ictus were included in this study. CK, serum PRL was measured at 0–1, 1–3, and 3–5 h after seizures.Results:Hundred subjects were studied for the role of serum PRL and serum CK in differentiating epileptic and PNES. The mean age was 42.24 years with a male:female ratio of 1.27:1. All patients of generalized tonic–clonic seizures (GTCS), who presented within 1 h, had elevated PRL, whereas 75% of patients with partial seizures had elevated PRL within 1 h of presentation. Nearly 91.66% of patients with GTCS who presented within 1 h had elevated CPK, whereas 70% of patients with partial seizures had elevated CPK. None of the patients diagnosed with PNES showed rise in either of the markers.Conclusion:In the present study, none of the patients with PNES showed raise in either serum PRL or CK. However, there was no correlation between the types of seizure and PRL or serum CK levels.

show abstract

“…Patients who have more than two seizures in 12 h have progressively smaller elevations, presumably because stored PRL from the pituitary lactotrophs is exhausted. [ 7 11 12 ]…”

Section: Discussionmentioning

confidence: 99%

Role of Biomarkers in Differentiating New-onset Seizures from Psychogenic Nonepileptic Seizures

Javali

Acharya

Shah

et al. 2017

Journal of Neurosciences in Rural Practice

View full text Add to dashboard Cite

show abstract

“…It is one of the most common neurological disorders, with an incidence of 50/100,000 2 . However, a large number of seizures is triggered by other etiologies, and the differential diagnosis of epilepsy and these provoked attacks may be extremely difficult to handle among physicians 3 . A crucial report has revealed that 20% of followed patients diagnosed with epilepsy have been misdiagnosed 4 .…”

mentioning

confidence: 99%

Simultaneous electrocardiogram during routine electroencephalogram: arrhythmia rates through the eyes of the cardiologist

Önder

Tezer

Hekimsoy

et al. 2021

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Background: The importance of simultaneous 2-lead electrocardiogram (ECG) recording during routine electroencephalogram (EEG) has been reported several times on clinical grounds. Objective: To investigate arrhythmia rates detected by simultaneous 2-lead ECG in our patient sample undergoing routine EEG. Remarkably, we sought to assess the possible expansion of results with a more experienced interpretation of simultaneous ECG. Methods: Simultaneous 2-lead ECG recordings during routine EEG, performed between January and March, 2016, have been retrospectively analyzed by a cardiology specialist. In addition, EEG reports were screened with the keywords ‘arrhythmia, tachycardia, bradycardia, atrial fibrillation, extrasystole’ to evaluate the neurologist interpretation. Results: Overall, 478 routine EEG recordings were scanned. The mean age of the patients was 42.8±19.8 (16–95), with a sex ratio of 264/214 (F/M). In 80 (17%) patients, findings compatible with arrhythmia were identified on simultaneous ECG after a cardiologist's evaluation. The detected arrhythmia subtypes were: ventricular extrasystole (n=27; 5.6%), supraventricular extrasystole (n=23; 4.8%), tachycardia (n=9; 1.8%), prolonged QRS duration (n=7; 8.7%), atrial fibrillation (n=6; 1.2%), and block (n=6; 1.2%). On the other hand, keywords related to arrhythmia were present in 45 (9.4%) of EEG reports. The reported statements were tachycardia (3.3%), arrhythmia (2.5%), bradycardia (2.1%), and extrasystole (1.5%). Conclusions: A considerably high rate of arrhythmia cases was determined on simultaneous ECG during routine EEG after being interpreted by a cardiologist. However, the screening results of EEG reports revealed relatively low arrhythmia rates. These results suggest that the detection rates of ECG abnormalities during routine EEG may be potentially improved.

show abstract

“…The differential diagnosis between epilepsy and non-epileptic attack disorder can be particularly challenging and often requires the availability of a range of neurophysiological tests alongside clinical observation and other investigations (4). An effective care pathway for patients with non-epileptic attack disorder requires the contribution of a wide range of clinicians, often with different backgrounds and approaches (5).…”

Section: Neuropsychiatry and Neurophysiologymentioning

confidence: 99%

Neurophysiological investigations for the diagnosis of non-epileptic attack disorder in neuropsychiatry services: from safety standards to improved effectiveness

Cavanna

Seri

2016

Acta Neuropsychiatr.

View full text Add to dashboard Cite

show abstract

New thoughts on first seizure

Cited by 10 publications

References 13 publications

Role of Biomarkers in Differentiating New-onset Seizures from Psychogenic Nonepileptic Seizures

Role of Biomarkers in Differentiating New-onset Seizures from Psychogenic Nonepileptic Seizures

Simultaneous electrocardiogram during routine electroencephalogram: arrhythmia rates through the eyes of the cardiologist

Neurophysiological investigations for the diagnosis of non-epileptic attack disorder in neuropsychiatry services: from safety standards to improved effectiveness

Contact Info

Product

Resources

About