New Strategy for Detection of Subclinical Coronary Atherosclerosis in Asymptomatic Patients With Type 2 Diabetes Based on Cardiac Multi-Detector Computed Tomography and Treadmill Test

Jeong, Hae Chang; Kim, Inna; Park, Keun Ho; Sim, Doo Sun; Hong, Young Joon; Kim, Ju Han; Jeong, Myung Ho; Cho, Jeong Gwan; Park, Jong Chun; Kim, Yun‐Hyeon; Seon, Hyun Ju; Moon, Jae Dong; Ahn, Youngkeun

doi:10.1253/circj.cj-13-1038

Cited by 11 publications

(11 citation statements)

References 26 publications

(11 reference statements)

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“…[1][2][3][4][5][6] Epicardial adipose tissue (EAT), visceral fat deposited around the heart between the myocardium and visceral pericardium, is known to secrete several bioactive molecules including inflammatory cytokines. 7, 8 Several studies have reported that epicardial fat volume (EFV) measured on multi-detector CT (MDCT) is related to CAD and cardiovascular risk.…”

Section: Subjectsmentioning

confidence: 99%

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification　– Results From the CAESAR Study –

Kim

Kang

2015

Circ J

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Section: Subjectsmentioning

confidence: 99%

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification　– Results From the CAESAR Study –

Kim

Kang

2015

Circ J

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“…At the same time, the prevalence of obstructive CAD is nearly 25%, much higher than would be expected in the nondiabetic population (86–100). Halon et al (96) examined 427 asymptomatic diabetic patients and found coronary plaques in 77% of them and ≥50% stenosis in 1 or more vessels in 23%.…”

Section: Coronary Cta For Risk Stratification Of the Asymptomatic mentioning

confidence: 81%

Noninvasive Cardiovascular Risk Assessment of the Asymptomatic Diabetic Patient

Budoff

Raggi

Beller

et al. 2016

JACC: Cardiovascular Imaging

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Increased cardiovascular morbidity and mortality in patients with type 2 diabetes is well established; diabetes is associated with at least a 2-fold increased risk of coronary heart disease. Approximately two-thirds of deaths among persons with diabetes are related to cardiovascular disease. Previously, diabetes was regarded as a “coronary risk equivalent,” implying a high 10-year cardiovascular risk for every diabetes patient. Following the original study by Haffner et al., multiple studies from different cohorts provided varying conclusions on the validity of the concept of coronary risk equivalency in patients with diabetes. New guidelines have started to acknowledge the heterogeneity in risk and include different treatment recommendations for diabetic patients without other risk factors who are considered to be at lower risk. Furthermore, guidelines have suggested that further risk stratification in patients with diabetes is warranted before universal treatment. The Imaging Council of the American College of Cardiology systematically reviewed all modalities commonly used for risk stratification in persons with diabetes mellitus and summarized the data and recommendations. This document reviews the evidence regarding the use of noninvasive testing to stratify asymptomatic patients with diabetes with regard to coronary heart disease risk and develops an algorithm for screening based on available data.

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“…La prevalencia de enfermedad coronaria asintomática (ECA) en pacientes con DM2 varía considerablemente entre estudios, pero en general es alta: en Corea, Jeong et al (16) encontraron algún grado de enfermedad aterosclerótica coronaria en 49% de este tipo de diabéticos por medio de angiografía coronaria por tomografía axial computarizada (ACTAC); en Dinamarca, Funck et al (17) la evidenciaron en el 76% de los evaluados por el mismo método; por su parte, Halon et al (18) en Israel y Lee et al (19) en Corea la evidenciaron en el 79% de los evaluados.…”

Section: Discusión Prevalencia De Enfermedad Coronaria Asintomáticaunclassified

Enfermedad coronaria asintomática en pacientes con diabetes mellitus tipo 2

Díaz¹,

León²,

Mogollón³

2019

Rev. Sal. Bosq

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Introducción: la enfermedad coronaria es una de las principales causas de morbimortalidad a nivel mundial; se sabe que la diabetes mellitus tipo 2 (DM2) es un factor de riesgo importante para esta patología y que puede producir una forma asintomática o con manifestaciones atípicas. Objetivos: exponer los principales datos epidemiológicos, pronósticos y determinantes de la enfermedad coronaria asintomática en DM2 y discutir las formas de tamización y su utilidad en diabéticos asintomáticos. Materiales y métodos: se realizó una búsqueda en PubMed, LILACS y SciELO usando las palabras clave “Diabetes Mellitus, type 2”, “Coronary disease”, “Coronary Artery Disease”, “Coronary Vessels”, “Atherosclerosis”, “Arteriosclerosis”, “Asymptomatic Diseases”, “Asymptomatic”, “Silent” y “Myocardcial infarction”, ajustando la búsqueda según las necesidades de cada base de datos. Se incluyeron artículos que cumplieran los criterios de inclusión y no los de exclusión, a consideración de los autores, así como algunas referencias adicionales. Resultados: se revisó el título y resumen de 504 artículos encontrados en las bases de datos, tras lo cual se escogieron 81 para su lectura total. De ellos, 56 fueron incluidos, así como 48 publicaciones adicionales conocidas por los autores o referenciados en las artículos leídos, lo que dio un total de 104 artículos incluidos en la revisión final. Conclusiones: los pacientes con DM2 presentan altas prevalencias de enfermedad coronaria asintomática que aumentan en presencia de otros factores de riesgo cardiovascular o de mayor duración o progresión de la DM2. Si bien existen varios métodos anatómicos o funcionales para su detección, la tamización de esta población no ha mostrado beneficio alguno, por lo que no puede recomendarse de rutina en asintomáticos.

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New Strategy for Detection of Subclinical Coronary Atherosclerosis in Asymptomatic Patients With Type 2 Diabetes Based on Cardiac Multi-Detector Computed Tomography and Treadmill Test

Cited by 11 publications

References 26 publications

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification　– Results From the CAESAR Study –

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification　– Results From the CAESAR Study –

Noninvasive Cardiovascular Risk Assessment of the Asymptomatic Diabetic Patient

Enfermedad coronaria asintomática en pacientes con diabetes mellitus tipo 2

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New Strategy for Detection of Subclinical Coronary Atherosclerosis in Asymptomatic Patients With Type 2 Diabetes Based on Cardiac Multi-Detector Computed Tomography and Treadmill Test

Cited by 11 publications

References 26 publications

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification – Results From the CAESAR Study –

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification – Results From the CAESAR Study –

Noninvasive Cardiovascular Risk Assessment of the Asymptomatic Diabetic Patient

Enfermedad coronaria asintomática en pacientes con diabetes mellitus tipo 2

Contact Info

Product

Resources

About

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification　– Results From the CAESAR Study –

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification　– Results From the CAESAR Study –