New simple prognostic score for primary biliary cirrhosis: Albumin‐bilirubin score

Chan, Anthony W.H.; Chan, Ronald Cheong Kin; Wong, Grace Lai–Hung; Wong, Vincent Wai‐Sun; Choi, Pui–Wah; Chan, Henry Lik‐Yuen; To, Ka‐Fai

doi:10.1111/jgh.12938

Cited by 103 publications

(86 citation statements)

References 23 publications

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“…An ALBI score of >− 2.118 may be inappropriate for the use of sorafenib. More recently, a retrospective study also compared the prognostic performance of ALBI versus Child-Pugh, the model for end-stage liver disease (MELD), Mayo risk, Yale, European, and Newcastle scores in patients with primary biliary cirrhosis (4). Compared with other scores, the ALBI score had the highest prognostic performance in such patients.…”

Section: Introductionmentioning

confidence: 99%

Albumin-bilirubin score for predicting the in-hospital mortality of acute upper gastrointestinal bleeding in liver cirrhosis: A retrospective study

Zou

Qi²,

Zhu³

et al. 2016

Turk J Gastroenterol

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Section: Introductionmentioning

confidence: 99%

Albumin-bilirubin score for predicting the in-hospital mortality of acute upper gastrointestinal bleeding in liver cirrhosis: A retrospective study

Zou

Qi²,

Zhu³

et al. 2016

Turk J Gastroenterol

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“…The ALBI score may be used to evaluate the liver function damage and prognosis of patients with liver cancer (12,13). This score has been reported to have predictive value for in-hospital mortality in patients with primary biliary cirrhosis or LC combined with upper gastrointestinal bleeding (14,15). Few studies on the value of the ALBI score in assessing the conditions of liver function damage in various HBV-related liver diseases have been performed (16,17).…”

Section: Introductionmentioning

confidence: 99%

Value of the albumin‑bilirubin score in the evaluation of hepatitis B virus‑related acute‑on‑chronic liver failure, liver cirrhosis, and hepatocellular carcinoma

et al. 2018

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Abstract. The aim of the present study was to investigate the value of the albumin-bilirubin (ALBI) score in the assessment of the disease conditions of hepatitis B virus (HBV)-related acute-on-chronic liver failure (HBV-ACLF), HBV-related liver cirrhosis (HBV-LC) and HBV-related hepatocellular carcinoma (HBV-HCC). A total of 395 patients with HBV-ACLF, HBV-LC, or HBV-HCC were retrospectively studied. The ALBI, Child-Turcotte-Pugh (CTP), and Model for End-Stage Liver Disease (MELD) scores of the patients were calculated, and the relationships between the ALBI score and the CTP and MELD scores were investigated. Furthermore, the ALBI grading was tested for the evaluation of the severity and stages of HBV-ACLF, HBV-LC, and HBV-HCC, especially when classifying the clinical stages of HBV-ACLF. The mean ALBI scores of the HBV-ACLF, HBV-LC, and HBV-HCC patients were -1.17±0.55, -1.76±0.66 and -2.59±0.62, respectively; the mean CTP scores were 10.70±1. 81, 8.19±1.25 and 5.81±1.22, respectively; and the mean MELD scores were 19.93±7.44, 11.10±4.39 and 7.01±3.22, respectively. The ALBI scores were positively correlated with the CTP and MELD scores. The mean ALBI score and the frequency of grade 3 disease were higher in HBV-ACLF patients than in patients with HBV-LC or HBV-HCC. A later HBV-ACLF stage resulted in a higher frequency of ALBI grades of 3. In conclusion, ALBI scores exhibited parallel tendencies to the CTP and MELD scores in HBV-ACLF, HBV-LC, and HBV-HCC patients; thus, ALBI grading may be a simple but applicable method for the evaluation of the functional status of patients with HBV-related end-stage liver diseases.

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“…13 It is superior to Child-Pugh and MELD scores for predicting the occurrence of hepatic events in patients with primary biliary cholangitis. 14 The prognostic performance of the ALBI score was comparable with that of the CTP and MELD scores for predicting the IHM of AUGIB in liver cirrhosis. 15 The AIMS65 score was retrospectively validated in 32,507 patients.…”

Section: Introductionmentioning

confidence: 79%

Risk scoring systems to predict in-hospital mortality in patients with acute variceal bleeding due to HCV-induced liver cirrhosis

Hassanien

El-Ghannam

El-Talkawy

et al. 2018

Gastroenterol Insights

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This study was designed to validate and to compare accuracy of the prognostic scores; mainly Child Turcotte Pugh (CTP), creatinine-modified Child Turcotte Pugh (CTP-Cr), model for end-stage liver disease (MELD), albumin bilirubin score (ALBI), and AIMS65, for the predicting clinical outcomes in cirrhotic Egyptian patients presenting with acute variceal bleeding (AVB). Retrospective single center study involving 725 patients presenting with AVB due to liver cirrhosis and HCV infection either alone or mixed with HBV infection. In hospital mortality prognostic scores were calculated; mainly CTP, modified CTP-Cr, MELD, ALBI, AIMS65. The endpoint is either patient improvement or death. 725 patients were included over 1-year period. 547 (75%) survived and 178 (25%) died. Patients presented with hematemesis (515/71%), melena (120/16.5%) or hematemesis and melena (90/12.5%). Those with hematemesis for the first time were 241 (33%) and recurrent attacks were 484 (66.8%). The non-survivors had significantly more incidence of shock on presentation, more blood transfused units, history of NSAIDS intake, more ICU admission days and were more likely to be Childs C. Child, modified CTP-Cr, MELD, ALBI and ALMS65 scoring systems showed significant difference between survivors and nonsurvivors. Liver specific scores (Child, MELD) and gastrointestinal bleeding scoring systems (ALBI, AIMS65) are useful in predicting clinical outcomes of AVB in cirrhotic patients. CTP-Cr score had the highest prognostic capability of in hospital mortality. Presence of active bleeding at time of endoscopy, more complications, old age, shock and higher CPT-Cr score are additional independent predictors of in hospital mortality.

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New simple prognostic score for primary biliary cirrhosis: Albumin‐bilirubin score

Abstract: The ALBI score is readily derived from a blood test without using those factors evaluated subjectively or obtained by invasive procedures. It is an independent prognostic factor for PBC patients and provides better/similar prognostic performance compared with other prognostic scores.

Cited by 103 publications

References 23 publications

Albumin-bilirubin score for predicting the in-hospital mortality of acute upper gastrointestinal bleeding in liver cirrhosis: A retrospective study

Albumin-bilirubin score for predicting the in-hospital mortality of acute upper gastrointestinal bleeding in liver cirrhosis: A retrospective study

Value of the albumin‑bilirubin score in the evaluation of hepatitis B virus‑related acute‑on‑chronic liver failure, liver cirrhosis, and hepatocellular carcinoma

Risk scoring systems to predict in-hospital mortality in patients with acute variceal bleeding due to HCV-induced liver cirrhosis

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