New Sesquiterpenoids from the Fermented Broth of Termitomyces albuminosus and Their Anti-Acetylcholinesterase Activity

Li, Wei; Liu, Qian; Li, Shanren; Zheng, Yusheng

doi:10.3390/molecules24162980

Cited by 16 publications

(10 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous evidence-based analysis demonstrated that the termite nest contained large amounts of pharmaceutical agents, e.g., polysaccharides, sesquiterpenoids, cerebrosides, heteroglycans, isoflavonoids, etc. (Hua et al, 2015;Lee et al, 2018;Li et al, 2019;Zhao et al, 2019), most of which were well summarized in a previous review (Hsieh and Ju, 2018). Herein, we only compiled a general overview of the newly found active compounds from Termitomyces sp.…”

Section: Cockroach Ground Beetle and Termitementioning

confidence: 94%

A minireview of the medicinal and edible insects from the traditional Chinese medicine (TCM)

Zhang

Ouyang

et al. 2023

Front. Pharmacol.

View full text Add to dashboard Cite

Entomoceuticals define a subset of pharmaceuticals derived from insects. The therapeutic effect of insect-derived drugs has been empirically validated by the direct use of various folk medicines originating from three sources in particular: the glandular secretions of insects (e.g., silk, honey, venom), the body parts of the insect or the whole used live or by various processing (e.g., cooked, toasted, ground), and active ingredients extracted from insects or insect-microbe symbiosis. Insects have been widely exploited in traditional Chinese medicine (TCM) relative to other ethnomedicines, especially in the prospect of insect species for medicinal uses. It is noticeable that most of these entomoceuticals are also exploited as health food for improving immune function. In addition, some edible insects are rich in animal protein and have high nutritional value, which are used in the food field, such as insect wine, health supplements and so on. In this review, we focused on 12 insect species that have been widely used in traditional Chinese herbal formulae but have remained less investigated for their biological properties in previous studies. We also combined the entomoceutical knowledge with recent advances in insect omics. This review specifies the underexplored medicinal insects from ethnomedicine and shows their specific medicinal and nutritional roles in traditional medicine.

show abstract

Section: Cockroach Ground Beetle and Termitementioning

confidence: 94%

A minireview of the medicinal and edible insects from the traditional Chinese medicine (TCM)

Zhang

Ouyang

et al. 2023

Front. Pharmacol.

View full text Add to dashboard Cite

show abstract

“…Other two new cerebrosides, named termitomycesphins G (97) and H (98) were later isolated from this mushroom by the same research group [242]. Four new selinane-type sesquiterpenoids, named teucdiol C-F (see structures 99-102 in Figure 18), together with the known compounds teucdiol B (103) and epi-guaidiol A (104) were isolated by from a fermentation broth of T. albuminosus [243]; epiguaidiol A (104) showed potent anti-acetylcholinesterase activity in a dose-dependent manner [243]. Termitomyces albuminosus (Berk.)…”

Section: Termitomyces Albuminosus (Berk) R Heimmentioning

confidence: 97%

“…Termitomycesphins G (97) and H (98) (neuritogenic activity [242]). epi-Guaidiol A (104) (anti-acetylcholinesterase activity [243]). [263], Extract [266] Ribonuclease (inhibitory activity toward HIV-1 reverse transcriptase) [262].…”

Section: Thelephora Ganbajun M Zangmentioning

confidence: 99%

Bioactive Phytochemical Constituents of Wild Edible Mushrooms from Southeast Asia

et al. 2020

View full text Add to dashboard Cite

Mushrooms have a long history of uses for their medicinal and nutritional properties. They have been consumed by people for thousands of years. Edible mushrooms are collected in the wild or cultivated worldwide. Recently, mushroom extracts and their secondary metabolites have acquired considerable attention due to their biological effects, which include antioxidant, antimicrobial, anti-cancer, anti-inflammatory, anti-obesity, and immunomodulatory activities. Thus, in addition to phytochemists, nutritionists and consumers are now deeply interested in the phytochemical constituents of mushrooms, which provide beneficial effects to humans in terms of health promotion and reduction of disease-related risks. In recent years, scientific reports on the nutritional, phytochemical and pharmacological properties of mushroom have been overwhelming. However, the bioactive compounds and biological properties of wild edible mushrooms growing in Southeast Asian countries have been rarely described. In this review, the bioactive compounds isolated from 25 selected wild edible mushrooms growing in Southeast Asia have been reviewed, together with their biological activities. Phytoconstituents with antioxidant and antimicrobial activities have been highlighted. Several evidences indicate that mushrooms are good sources for natural antioxidants and antimicrobial agents

show abstract

“…The main chemical components include ergosterol and polysaccharide. Six sesquiterpenoids, teucdiol B-F, and epi-guaidiol A showing anti-acetylcholinesterase activity in a dose-dependent manner have been isolated from the fermented broth of T. albuminosus (Li et al, 2019). Furthermore, eight cerebrosides known as termitomycesphins A-H isolated from T. albuminosus exhibited neuritogenic activity against PC12 cells (Qi et al, 2000;Qu et al, 2012).…”

Section: Termitomyces Albuminosusmentioning

confidence: 99%

Main functional ingredients, nutritional, and medicinal values of common wild edible fungi: a review

Shen¹,

Wang²,

Liu³

et al. 2022

IFRJ

View full text Add to dashboard Cite

Common wild edible fungi are not only delicious but are also high in nutritional and medicinal values. They contain many functional ingredients such as polysaccharides, alkaloids, choline, triterpenes, essential amino acids, vitamins, and minerals as their chemical constituents. Seven species of common wild edible fungi were chosen for their main functional ingredients, nutritional values, and medicinal importance in this review.

show abstract

New Sesquiterpenoids from the Fermented Broth of Termitomyces albuminosus and Their Anti-Acetylcholinesterase Activity

Cited by 16 publications

References 30 publications

A minireview of the medicinal and edible insects from the traditional Chinese medicine (TCM)

A minireview of the medicinal and edible insects from the traditional Chinese medicine (TCM)

Bioactive Phytochemical Constituents of Wild Edible Mushrooms from Southeast Asia

Main functional ingredients, nutritional, and medicinal values of common wild edible fungi: a review

Contact Info

Product

Resources

About