New sesquiterpene polyol esters from the root bark of Pseudolarix kaempferi

Jiang, Hai‐Long; Ha, Wei; Yang, Jun‐Li; Shi, Yan‐Ping

doi:10.1016/j.phytol.2016.06.004

Cited by 4 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The 1 H and 13 C NMR data of 1 revealed (Table 1 ) an angular methyl ( δ H 0.74, δ C 9.9), a vinyl methyl ( δ H 1.70, δ C 22.2), two oxymethines ( δ H 3.44, δ C 77.1; δ H 4.06, δ C 70.4), and two terminal double bonds ( δ H 4.73, 5.11, δ C 103.4, 151.6; δ H 4.79, 4.91, δ C 110.9, 146.4). These observations suggested that 1 possessed a eudesmane framework with two hydroxy groups and two terminal double bonds [ 14 – 18 ]. From the HMBC experiment (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…The 1 H and 13 C NMR data of 2 demonstrated three methyls ( δ H 1.11, 1.22, 1.32; δ C 11.1, 29.2, 29.6), one oxymethine ( δ H 3.45; δ C 79.3), one oxygenated tertiary carbon ( δ C 74.4), and one terminal double bond ( δ H 4.54, 4.78; δ C 106.8, 149.3). These observations indicated 2 as an eudesmane sesquiterpenoid possessing two hydroxy groups and one terminal double bond [ 14 – 18 ]. Furthermore, its planer structure was constructed via HMBC experiment as shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

“…The main usage of this traditional Chinese medicine was to treat inflammation, headache, and vertigo and for the preparation of a bitter tea used for antibacterial, antioxidant, and anti-inflammatory purposes [ 13 ]. It has long been our goal to find more novel sesquiterpenoids from traditional Chinese herbs [ 14 – 18 ]. As part of this program, an investigation of an aqueous EtOH extract of the flowers of C. indicum afforded 2 further new sesquiterpenoids (Fig.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Yang

Liu

Shi

2019

Nat. Prod. Bioprospect.

Self Cite

View full text Add to dashboard Cite

The flowers of Chrysanthemum indicum, i.e. Ye-ju-hua recorded in the Chinese Pharmacopoeia, has been widely used in China as an important heat-clearing and detoxifying herb for the treatment of inflammation, headache, and vertigo. A phytochemical investigation of this herb has led to the isolation of two new eudesmane sesquiterpenoids, 7-epi-eudesm-4(15),11(13)-diene-1β,3β-diol (1) and 7-epi-1β-hydroxy-β-eudesmol (2). The molecular structures of these new sesquiterpenoids were established based on the comprehensive spectroscopic analyses, including NMR, MS, and IR, and comparing with the literatures.Graphical Abstract Electronic supplementary materialThe online version of this article (10.1007/s13659-019-0199-9) contains supplementary material, which is available to authorized users.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Yang

Liu

Shi

2019

Nat. Prod. Bioprospect.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Our research group has long been focused on the discovery of bioactive natural compounds from the traditional herbs cultivated in Northwestern China [12–16]. As part of this ongoing program, a phytochemical study on the roots of A. pendulum collected from Gansu province has been conducted.…”

Section: Introductionmentioning

confidence: 99%

Diterpenoid Alkaloids and One Lignan from the Roots of Aconitum pendulum Busch

Wang

Meng

Chai

et al. 2019

Nat. Prod. Bioprospect.

Self Cite

View full text Add to dashboard Cite

Diterpenoid alkaloids have neroprotective activity. Herein, three napelline-type diterpenoid alkaloids 1–3, two aconitine-type diterpenoid alkaloids 4–5, and one isoquinline-type alkaloid 6, as well as one lignan glycoside 7, have been isolated from the roots of Aconitum pendulum Busch. Compounds 1 and 7 were new compounds, and their chemical structures were determined on the basis of nuclear magnetic resonance (NMR) spectra and mass spectrometry analysis. A ThT assay revealed that compound 2 showed significant disaggregation potency on the Aβ1−42 aggregates.Graphical Abstract Electronic supplementary materialThe online version of this article (10.1007/s13659-019-00227-y) contains supplementary material, which is available to authorized users.

show abstract

Ultrasonic Cell Grinder Extraction of Cyperenoic Acid from Crotonis Crassifolii Radix and the Activity Assay of the Extract

Jiang

et al. 2022

ChemistrySelect

View full text Add to dashboard Cite

It is of great significance to achieve a high‐value usage of Chinese medicine residues. This study developed a green ultrasonic cell grinder extraction (UCGE) method has been developed for cyperenoic acid extraction from water decocted Crotonis Crassifolii Radix. The response surface methodology was introduced for the experimental design. The optimum conditions were as follows: 52 % ethanol concentration, 28 : 1 mL/g ratio of solution‐to‐solid, 500 W extraction power, and 28 min extraction time. Anti‐inflammatory test was performed to investigate the medicinal uses of the extract from the herb residue. The microstructure of the extracted samples was also investigated using scanning electron microscopy to understand the extraction mechanism. A higher extraction yield of 1.016 mg/g and better anti‐inflammatory activity were obtained under UCGE compared to a conventional solvent extraction. Meanwhile, the sample structure was seriously damaged by UCGE. The results show that UCGE is a promising green and efficient technology for extracting functional components, and has great potential in recycling waste resources.

show abstract

New sesquiterpene polyol esters from the root bark of Pseudolarix kaempferi

Cited by 4 publications

References 17 publications

Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Diterpenoid Alkaloids and One Lignan from the Roots of Aconitum pendulum Busch

Ultrasonic Cell Grinder Extraction of Cyperenoic Acid from Crotonis Crassifolii Radix and the Activity Assay of the Extract

Contact Info

Product

Resources

About