New records of nail and skin infection due to<i>Onychocola canadensis</i>and description of its teleomorph<i>Arachnomyces nodosetosus</i>sp. nov.

Sigler, Lynne; Abbott, Sean P.; Woodgyer, Alan

doi:10.1080/02681219480000351

Cited by 38 publications

(18 citation statements)

References 8 publications

(16 reference statements)

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“…Older cultures may form irregularly and scarcely septate, broad, thick‐walled, coiled or spiraled, brownish and knobby hyphae of varying width (1). Sigler et al (2) have recently demonstrated the presence of its teleomorph Arachnomyces nodosetosus sp. nov by mating experiments after several months of incubation in the laboratory.…”

Section: Discussionmentioning

confidence: 99%

“…The fungus was initially considered to be classifiable in the genus Scytalidium due to its formation of hyaline arthroconidia, similarities of clinical features, appearance in direct microscopy, and isolation from human nail. However, O. canadensis differs from Scytalidium species in its slower daily growth rate, persistance of conidial chains, susceptibility to antifungals, resistance to cycloheximide, and presence of coiled or spirrailed, knobbed, brown hyphae in old cultures (1, 2). A total of 30 mycologically confirmed cases of nail and skin infection due to O. canadensis have been reported from Canada, New Zealand, France, and the United Kingdom (3).…”

Section: Introductionmentioning

confidence: 99%

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Cutaneous Hyalohyphomycosis and Onychomycosis Caused by Onychocola canadensis: Report of the First Case from Turkey

Erbağcı

Balcı

Erkılıç

et al. 2002

The Journal of Dermatology

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We present the first Turkish case of skin and nail infection due to Onychocola canadensis in an otherwise healthy farmer who frequently worked barefoot on soil. Cutaneous involvement consisted of scaly and hyperkeratotic lesions resembling tinea pedis, erythematous plaques, and dermal papulonodules of various sizes simulating Majocchi's granuloma. Repeated cultures from nail plates, skin scrapings and needle aspiration materials from papules or nodules all yielded the same mold on Sabouroud dextrose media with and without cycloheximide, trichophyton agar, and potato dextrose agar at 26 degrees C. The causal isolate was identified as Onychocola canadensis Sigler gen. et sp. nov., a slow-growing arthroconidial hyphomycete, on the basis of its colonial and microscopic morphology. While skin lesions were responsive to daily itraconazole in a dose of 200 mg for three months, the onychomycosis was resistant to therapy. To our knowledge, this is the first presentation of O. canadensis as the cause of cutaneous hyalohyphomycosis to date.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cutaneous Hyalohyphomycosis and Onychomycosis Caused by Onychocola canadensis: Report of the First Case from Turkey

Erbağcı

Balcı

Erkılıç

et al. 2002

The Journal of Dermatology

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“…Am Ende dieser Behandlung war jedoch das Nativpräparat immer noch positiv, auch wuchs in der Kultur nach wie vor O. canadensis [24]. Bei einem weiteren Patienten kam Ketoconazol oral zum Einsatz, musste jedoch wegen Hepatotoxizität abgesetzt werden.…”

Section: Maldi-tofmassenspektrometrieunclassified

“…Daraufhin wurde weiter topisch mit Nystatin behandelt, worunter sich das Erscheinungsbild der Nägel nur leicht besserte. Die chirurgische Extraktion des Nagels bei einem 83-jährigen Mann aus Neuseeland führte nicht zur Heilung, die Nägel wuchsen nach der Extraktion unverändert wie zuvor mit Pilzbefall [24]. Nicht erfolgreich waren beispielsweise auch das Auftragen von TerbinafinCreme und die orale Gabe von Terbinafin, gefolgt von Itraconazol [27].…”

Section: Maldi-tofmassenspektrometrieunclassified

Onychocola canadensis Sigler bei Onychomykose

et al. 2016

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Moulds or non-dermatophyte moulds (NDM) are being increasingly isolated as causative agent of onychomycoses. Known causes of a NDM-OM are Scopulariopsis brevicaulis, Fusarium, Aspergillus, Acremonium, Neoscytalidium dimidiatum, Arthrographis kalrae, and Chaetomium. In this article, 5 patients with suspected nail infection due to Onychocola canadensis are reported for the first time in Germany. Systemic antifungal agents are not considered to be effective in NDM onychomycosis. In individual cases, however, terbinafine seems to be effective in Onychocola canadensis infection of the nails. Treatment of choice represents, however, nontraumatic nail avulsion using 40 % urea ointment followed by antifungal nail lacquer with ciclopirox olamine or amorolfine.

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“…Salmon was recently reviewed by Abbott et al (1996) (Massee and Salmon, 1902;Malloch and Cain, 1970;Sigler et al, 1994). Salmon was recently reviewed by Abbott et al (1996) (Massee and Salmon, 1902;Malloch and Cain, 1970;Sigler et al, 1994).…”

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confidence: 99%