New Radiohalogenation: An Overview

Coenen, Heinz H.

doi:10.1007/978-94-009-4297-4_13

Cited by 12 publications

(9 citation statements)

References 80 publications

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“…Coenen (1986), using a modified disadvantagement-score adapted to the Dutch housing market, found only weak correlations between both original and adapted scores and social problems. Although practical experience and data from scientific research in The Netherlands seem to confirm Coleman's view, other factors also proved to be important.…”

Section: E Attractivitymentioning

confidence: 99%

Residential crime and environmental design

Voordt¹

1987

Neth. J. of Housing and environment Res.

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Section: E Attractivitymentioning

confidence: 99%

Residential crime and environmental design

Voordt¹

1987

Neth. J. of Housing and environment Res.

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“…Nevertheless, the radioiodo-dediazonisation was earlier successfully applied for the preparation of a series of tracers even under n.c.a. conditions as summarised in earlier reviews together with a detailed discussion of the mechanistic features of the reaction [99,100]. Recently, the method was used to prepare a radioiodinated derivative of spiperone [40] and various benzamides [88,101] from their corresponding diazonium precursors.…”

Section: Cu(i)-assisted Radioiodinationmentioning

confidence: 99%

Radioionidation Reactions for Radio Pharmaceuticals

Coenen¹,

Mertens²,

Mazieère³

2006

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HB) ISBN-13 978-1-4020-4560-8 (HB) ISBN-10 1-4020-4561-1 (e-book) Published by Springer, All rights reserved. ß 2006 Springer No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work.Printed in the Netherlands. PREFACEFounded in 1971, COST is an intergovernmental framework for European Cooperation in the field of scientific and technical research, allowing the coordination of nationally funded research on a European level. COST actions cover basic and precompetitive research, as well as activities of public utility. The goal of COST is to ensure that Europe holds a strong position in the field of scientific and technical research for peaceful purposes, by increasing European cooperation and interaction.COST consists in actions, the duration of which is generally 4 years. Two actions, COST B3 entitled ''Development of New Radiotracers and Methods of Quality Assurance for Nuclear Medicine Applications'' and COST B12 entitled ''Radiotracers for In Vivo Assessment of Biological Functions'', which have been devoted to radiopharmaceutical chemistry and radiopharmaceutical validation, were successfully completed.Radiochemical methodology constitutes the most important base for successful in vivo functional imaging in nuclear medicine. For single-photon emission tomography (SPET) imaging, radioiodination methodology allows the development of potent radiotracers, and several of them are presently in clinical routine.Many previous publications have tackled the specific problems of radioiodination, but the time for a state-of-the-art book seemed right now since this field has advanced over the last 30 years to reach a level where guidelines and expert systems can be suggested for the main methodological aspects. This book has emerged from an original idea during the course of COST Action B3 and was developed during the course of COST Action B12 with the help of many recognised European experts in the field. Sincere thanks to all of them for their very precious support, advice and contributions.The authors gratefully acknowledge the support of COST, which, all along the duration of the actions, has encouraged the preparation and the finalisation of a collective textbook.

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“…There is a longstanding interest in the radioisotopes of bromine for application in nuclear medicine [1][2][3][4][5]. This is based on their versatile decay properties and covalent chemical bonding.…”

Section: Introductionmentioning

confidence: 99%

“…Further, it can rather easily be oxidised in situ, thus facilitating n.c.a. electrophilic substitution reactions in vinyl and aryl positions [5]. The lighter isotope 75 Br with its short halflife, high positron emission intensity and low positron energy, had been extensively evaluated up to about 1990 for *Author for correspondence (E-mail: i.spahn@fz-juelich.de).…”

Section: Introductionmentioning

confidence: 99%

New cross section measurements for production of the positron emitters 75Br and 76Br via intermediate energy proton induced reactions

et al. 2009

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75 Br / 76 Br / Intermediate energy / Proton induced reactions / Excitation function / Integral yield Summary. The radionuclides 75 Br and 76 Br are of considerable interest for application in Positron Emission Tomography (PET). For their production so far mostly low-energy or low-yield production processes have been employed. In this work the production of both isotopes was investigated using intermediate energy proton induced reactions and enriched target materials. Cross section data of the 77,78,80 Se( p, xn) 75 Br processes were measured up to 66 MeV and those of the 77,78,80 Se( p, xn) 76 Br processes up to 85 MeV. The measured excitation functions were compared with calculated results of the nuclear model code ALICE-IPPE. From the experimental excitation curves, thick target yields were calculated. They are fairly high over the investigated intermediate energy ranges. The production possibilities of 75 Br and 76 Br via various routes and the radionuclidic impurities associated with them are discussed.

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New Radiohalogenation: An Overview

Cited by 12 publications

References 80 publications

Residential crime and environmental design

Residential crime and environmental design

Radioionidation Reactions for Radio Pharmaceuticals

New cross section measurements for production of the positron emitters 75Br and 76Br via intermediate energy proton induced reactions

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